4-Hydroxy-2-nonenal Induces Apoptosis by Inhibiting AKT Signaling in Human Osteosarcoma Cells
The onset of lipid peroxidation within cellular membranes is associated with changes in their physiochemical properties and enzymatic dysfunction of the membrane environment. There are increasing bodies of evidence indicating that aldehydic molecules generated endogenously during the process of lipi...
Saved in:
| Main Authors: | Guang-rong Ji, Nai-chun Yu, Xiang Xue, Zong-guang Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/873525 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
4-Hydroxy-2-nonenal causes nuclear accumulation of p62 by inhibiting Xpo1 and promoting the proteolytic pathway in the nucleus.
by: Emi Kayama, et al.
Published: (2025-01-01) -
Oxidative Stress and 4-hydroxy-2-nonenal (4-HNE): Implications in the Pathogenesis and Treatment of Aging-related Diseases
by: Yanling Li, et al.
Published: (2022-01-01) -
Fatty acids are key in 4-hydroxy-2-nonenal-mediated activation of uncoupling proteins 1 and 2.
by: Elena A Malingriaux, et al.
Published: (2013-01-01) -
Downregulation of PRKCI inhibits osteosarcoma cell growth by inactivating the Akt/mTOR signaling pathway
by: Liujing Qu, et al.
Published: (2024-07-01) -
Correction: Downregulation of PRKCI inhibits osteosarcoma cell growth by inactivating the Akt/mTOR signaling pathway
by: Liujing Qu, et al.
Published: (2025-07-01)