A rare clinical presentation of COVID 19: opsoclonus-myoclonus ataxia syndrome

Introduction: Coronavirus disease 2019 (COVID-19) can have symptoms like many neurological diseases, and one of the rare forms of these presentations is opsoclonus-myoclonus ataxia syndrome (OMAS). The pathogenesis of OMAS in adults has not been clearly elucidated and OMAS can be fatal. Case pres...

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Main Authors: Adalet Altunsoy, Nizamettin Kemirtlek, Halime Araz, Ebru Bilge Dirik, Esragül Akıncı
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2024-02-01
Series:Journal of Infection in Developing Countries
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Online Access:https://jidc.org/index.php/journal/article/view/17927
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author Adalet Altunsoy
Nizamettin Kemirtlek
Halime Araz
Ebru Bilge Dirik
Esragül Akıncı
author_facet Adalet Altunsoy
Nizamettin Kemirtlek
Halime Araz
Ebru Bilge Dirik
Esragül Akıncı
author_sort Adalet Altunsoy
collection DOAJ
description Introduction: Coronavirus disease 2019 (COVID-19) can have symptoms like many neurological diseases, and one of the rare forms of these presentations is opsoclonus-myoclonus ataxia syndrome (OMAS). The pathogenesis of OMAS in adults has not been clearly elucidated and OMAS can be fatal. Case presentation: We present a 71-year-old male patient who was admitted to the emergency department with complaints of involuntary tremor-like movements in his hands, feet and mouth, and speech impediment for three days, and was followed up with COVID-19. The patient was diagnosed with OMAS and clonazepam treatment was started. He died three days later due to respiratory arrest. Our case is the first case diagnosed with COVID-19-associated OMAS in Turkey. Discussion: OMAS has no definitive treatment. Early diagnosis and initiation of corticosteroids and intravenous immunoglobulin (IVIG) therapy, if necessary, can be life-saving. In COVID-19 patients with unexplained clinical findings, awareness of different and rare diseases and a multidisciplinary approach has vital importance.
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institution OA Journals
issn 1972-2680
language English
publishDate 2024-02-01
publisher The Journal of Infection in Developing Countries
record_format Article
series Journal of Infection in Developing Countries
spelling doaj-art-1f8c062ca9024ec6ab5e2a4cfb431b252025-08-20T02:14:20ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802024-02-01180210.3855/jidc.17927A rare clinical presentation of COVID 19: opsoclonus-myoclonus ataxia syndromeAdalet Altunsoy0Nizamettin Kemirtlek1Halime Araz2Ebru Bilge Dirik3Esragül Akıncı4University of Health Sciences, Gulhane Medical School, Ankara, TurkeyDepartment of Infectious Diseases and Clinical Microbiology, Ankara City Hospital, Ankara, TurkeyDepartment of Infectious Diseases and Clinical Microbiology, Ankara City Hospital, Ankara, TurkeyDepartment of Neurology, Ankara City Hospital, TurkeyUniversity of Health Sciences, Gulhane Medical School, Ankara, Turkey Introduction: Coronavirus disease 2019 (COVID-19) can have symptoms like many neurological diseases, and one of the rare forms of these presentations is opsoclonus-myoclonus ataxia syndrome (OMAS). The pathogenesis of OMAS in adults has not been clearly elucidated and OMAS can be fatal. Case presentation: We present a 71-year-old male patient who was admitted to the emergency department with complaints of involuntary tremor-like movements in his hands, feet and mouth, and speech impediment for three days, and was followed up with COVID-19. The patient was diagnosed with OMAS and clonazepam treatment was started. He died three days later due to respiratory arrest. Our case is the first case diagnosed with COVID-19-associated OMAS in Turkey. Discussion: OMAS has no definitive treatment. Early diagnosis and initiation of corticosteroids and intravenous immunoglobulin (IVIG) therapy, if necessary, can be life-saving. In COVID-19 patients with unexplained clinical findings, awareness of different and rare diseases and a multidisciplinary approach has vital importance. https://jidc.org/index.php/journal/article/view/17927COVID-19opsoclonus-myoclonus ataxia syndromecorticosteroidsintravenous immunoglobulinIVIG
spellingShingle Adalet Altunsoy
Nizamettin Kemirtlek
Halime Araz
Ebru Bilge Dirik
Esragül Akıncı
A rare clinical presentation of COVID 19: opsoclonus-myoclonus ataxia syndrome
Journal of Infection in Developing Countries
COVID-19
opsoclonus-myoclonus ataxia syndrome
corticosteroids
intravenous immunoglobulin
IVIG
title A rare clinical presentation of COVID 19: opsoclonus-myoclonus ataxia syndrome
title_full A rare clinical presentation of COVID 19: opsoclonus-myoclonus ataxia syndrome
title_fullStr A rare clinical presentation of COVID 19: opsoclonus-myoclonus ataxia syndrome
title_full_unstemmed A rare clinical presentation of COVID 19: opsoclonus-myoclonus ataxia syndrome
title_short A rare clinical presentation of COVID 19: opsoclonus-myoclonus ataxia syndrome
title_sort rare clinical presentation of covid 19 opsoclonus myoclonus ataxia syndrome
topic COVID-19
opsoclonus-myoclonus ataxia syndrome
corticosteroids
intravenous immunoglobulin
IVIG
url https://jidc.org/index.php/journal/article/view/17927
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