Schistosomal cryoglobulinemia associated with vasculitis and glomerulonephritis Case report
Schistosomiasis is an endemic, widespread disease in the subtropics and is a major cause of morbidity in developing countries. This is a report of a patient with a high titer of cryoglobulins composed of monoclonal IgM and anti-schistosoma IgG adult worm antibodies. This was associated with vasculit...
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PAGEPress Publications
2014-08-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
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| Online Access: | https://mjhid.org/index.php/mjhid/article/view/1931 |
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| author | Mohamed M NasrAllah |
| author_facet | Mohamed M NasrAllah |
| author_sort | Mohamed M NasrAllah |
| collection | DOAJ |
| description | Schistosomiasis is an endemic, widespread disease in the subtropics and is a major cause of morbidity in developing countries. This is a report of a patient with a high titer of cryoglobulins composed of monoclonal IgM and anti-schistosoma IgG adult worm antibodies. This was associated with vasculitis and membranoproliferative glomerulonephritis. Improvement was noted after treatment with steroids and cyclophosphamide. This case presents 3 novel findings: first, it is the first documentation, that we could trace, of a clear link between schistosomiasis and type II “essential” mixed cryoglobulinemia in humans where anti-schostosomal antibodies form the IgG component of the cryoglobulins. Second, it reports vasculitis associated with the shcistosomal cryoglobulins and finally it is a uniquel report of shcistosomal glomerulopathy responsive to immune suppression. |
| format | Article |
| id | doaj-art-1f85029ffa7e46d19efa7894e8ff5baf |
| institution | DOAJ |
| issn | 2035-3006 |
| language | English |
| publishDate | 2014-08-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-1f85029ffa7e46d19efa7894e8ff5baf2025-08-20T02:57:56ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062014-08-011Schistosomal cryoglobulinemia associated with vasculitis and glomerulonephritis Case reportMohamed M NasrAllah0Department of Nephrology, Kasr AlAiny School of Medicine, Cairo UniversitySchistosomiasis is an endemic, widespread disease in the subtropics and is a major cause of morbidity in developing countries. This is a report of a patient with a high titer of cryoglobulins composed of monoclonal IgM and anti-schistosoma IgG adult worm antibodies. This was associated with vasculitis and membranoproliferative glomerulonephritis. Improvement was noted after treatment with steroids and cyclophosphamide. This case presents 3 novel findings: first, it is the first documentation, that we could trace, of a clear link between schistosomiasis and type II “essential” mixed cryoglobulinemia in humans where anti-schostosomal antibodies form the IgG component of the cryoglobulins. Second, it reports vasculitis associated with the shcistosomal cryoglobulins and finally it is a uniquel report of shcistosomal glomerulopathy responsive to immune suppression.https://mjhid.org/index.php/mjhid/article/view/1931CryoglobulinemiaScistosoma mansoniparasitepost infectious glomerulonephritis |
| spellingShingle | Mohamed M NasrAllah Schistosomal cryoglobulinemia associated with vasculitis and glomerulonephritis Case report Mediterranean Journal of Hematology and Infectious Diseases Cryoglobulinemia Scistosoma mansoni parasite post infectious glomerulonephritis |
| title | Schistosomal cryoglobulinemia associated with vasculitis and glomerulonephritis Case report |
| title_full | Schistosomal cryoglobulinemia associated with vasculitis and glomerulonephritis Case report |
| title_fullStr | Schistosomal cryoglobulinemia associated with vasculitis and glomerulonephritis Case report |
| title_full_unstemmed | Schistosomal cryoglobulinemia associated with vasculitis and glomerulonephritis Case report |
| title_short | Schistosomal cryoglobulinemia associated with vasculitis and glomerulonephritis Case report |
| title_sort | schistosomal cryoglobulinemia associated with vasculitis and glomerulonephritis case report |
| topic | Cryoglobulinemia Scistosoma mansoni parasite post infectious glomerulonephritis |
| url | https://mjhid.org/index.php/mjhid/article/view/1931 |
| work_keys_str_mv | AT mohamedmnasrallah schistosomalcryoglobulinemiaassociatedwithvasculitisandglomerulonephritiscasereport |