PRAME immunohistochemistry distinguishes nodal nevi from metastatic melanoma

PRAME immunohistochemistry distinguishes nodal nevi from metastatic melanoma

Abstract Background Preferentially expressed antigen in melanoma (PRAME) is a promising immunohistochemical marker for distinguishing benign from malignant melanocytic lesions in lymph node deposits. Objective To evaluate PRAME expression in metastatic melanomas and nevi found in the sentinel lymph...

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Main Authors: Hortência Gomes da Silveira, Hercilio Fronza Junior, Larissa D’Espirro de Souza Campos, Jaqueline Stall, Rodrigo Blasius, Camila Kricheski, Bruna Louise Silva, Paulo Henrique Condeixa de França, Karina Munhoz de Paula Alves Coelho
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Surgical and Experimental Pathology
Subjects:
PRAME
Immunohistochemistry
Metastatic melanoma
Melanocytic nevi
Sentinel lymph nodes
Online Access:https://doi.org/10.1186/s42047-024-00171-3
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