New Piperazine Derivatives Synthesized from Thio-Substituted Polyhalogeno-2-nitro-1,3-butadienes

It is known that polyhalogeno-nitro-1,3-butadienes are important starting materials for the synthesis of polyfunctionalized bioactive heterocycles. Novel N,S-substituted nitrobutadienes (4a-j) were synthesized from the reaction of the monothio-substituted nitrodiene derivatives (2a) and (2b) with so...

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Main Authors: S. Goksin Aydinli, Cemil Ibis
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2010/605760
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author S. Goksin Aydinli
Cemil Ibis
author_facet S. Goksin Aydinli
Cemil Ibis
author_sort S. Goksin Aydinli
collection DOAJ
description It is known that polyhalogeno-nitro-1,3-butadienes are important starting materials for the synthesis of polyfunctionalized bioactive heterocycles. Novel N,S-substituted nitrobutadienes (4a-j) were synthesized from the reaction of the monothio-substituted nitrodiene derivatives (2a) and (2b) with some piperazine derivatives. These new compounds are stable and the structures of these products were characterized by spectroscopic data. The structure of the novel N,S-substituted nitrodiene compound (4g) synthesized in this study was also elucidated by single crystal x-ray analysis.
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id doaj-art-1f6d44b36fbe4121bcd1458f92d1692d
institution Kabale University
issn 0973-4945
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publishDate 2010-01-01
publisher Wiley
record_format Article
series E-Journal of Chemistry
spelling doaj-art-1f6d44b36fbe4121bcd1458f92d1692d2025-08-20T03:54:36ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-01741498150610.1155/2010/605760New Piperazine Derivatives Synthesized from Thio-Substituted Polyhalogeno-2-nitro-1,3-butadienesS. Goksin Aydinli0Cemil Ibis1Faculty of Engineering, Department of Chemistry, Istanbul University, 34320 Avcilar, Istanbul, TurkeyFaculty of Engineering, Department of Chemistry, Istanbul University, 34320 Avcilar, Istanbul, TurkeyIt is known that polyhalogeno-nitro-1,3-butadienes are important starting materials for the synthesis of polyfunctionalized bioactive heterocycles. Novel N,S-substituted nitrobutadienes (4a-j) were synthesized from the reaction of the monothio-substituted nitrodiene derivatives (2a) and (2b) with some piperazine derivatives. These new compounds are stable and the structures of these products were characterized by spectroscopic data. The structure of the novel N,S-substituted nitrodiene compound (4g) synthesized in this study was also elucidated by single crystal x-ray analysis.http://dx.doi.org/10.1155/2010/605760
spellingShingle S. Goksin Aydinli
Cemil Ibis
New Piperazine Derivatives Synthesized from Thio-Substituted Polyhalogeno-2-nitro-1,3-butadienes
E-Journal of Chemistry
title New Piperazine Derivatives Synthesized from Thio-Substituted Polyhalogeno-2-nitro-1,3-butadienes
title_full New Piperazine Derivatives Synthesized from Thio-Substituted Polyhalogeno-2-nitro-1,3-butadienes
title_fullStr New Piperazine Derivatives Synthesized from Thio-Substituted Polyhalogeno-2-nitro-1,3-butadienes
title_full_unstemmed New Piperazine Derivatives Synthesized from Thio-Substituted Polyhalogeno-2-nitro-1,3-butadienes
title_short New Piperazine Derivatives Synthesized from Thio-Substituted Polyhalogeno-2-nitro-1,3-butadienes
title_sort new piperazine derivatives synthesized from thio substituted polyhalogeno 2 nitro 1 3 butadienes
url http://dx.doi.org/10.1155/2010/605760
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