Echocardiographic findings and subsequent risk of native valve endocarditis
Aim: The association of echocardiographic findings and subsequent risk of left-sided native valve endocarditis (LS-NVE) is undefined. The aim of this study was to determine if transthoracic echocardiography (TTE) measurements are associated with the subsequent development of LS-NVE in patients witho...
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Open Exploration Publishing Inc.
2024-09-01
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| Series: | Exploration of Cardiology |
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| Online Access: | https://www.explorationpub.com/uploads/Article/A101234/101234.pdf |
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| author | Juan A. Quintero-Martinez Joya-Rita Hindy Hector R. Villarraga Brian D. Lahr Mark J. Dayer Martin H. Thornhill John C. O’Horo Hector I. Michelena Nandan S. Anavekar Parham Sendi Daniel C. DeSimone Larry M. Baddour |
| author_facet | Juan A. Quintero-Martinez Joya-Rita Hindy Hector R. Villarraga Brian D. Lahr Mark J. Dayer Martin H. Thornhill John C. O’Horo Hector I. Michelena Nandan S. Anavekar Parham Sendi Daniel C. DeSimone Larry M. Baddour |
| author_sort | Juan A. Quintero-Martinez |
| collection | DOAJ |
| description | Aim: The association of echocardiographic findings and subsequent risk of left-sided native valve endocarditis (LS-NVE) is undefined. The aim of this study was to determine if transthoracic echocardiography (TTE) measurements are associated with the subsequent development of LS-NVE in patients without cardiac predisposing conditions. Methods: Institutional databases were evaluated for adults diagnosed with LS-NVE from 2008 to 2020. Patients with prosthetic valves, cardiovascular implantable electronic devices, intracardiac devices, injection drug use, and predisposing cardiac conditions were excluded. Only patients who had a TTE performed 6 months to 3 years before the development of LS-NVE were included as cases. Controls were patients within the same Mayo location with a TTE report and were matched in a 1:3 ratio according to age, gender, Charlson comorbidity index, and echocardiography date. Results: There were 148 cases and 431 matched controls. As compared to controls, infective endocarditis (IE) cases had a higher prevalence of diabetes mellitus (46.6% vs. 30.4%) and chronic kidney disease (46.6% vs. 28.1%) (P < 0.001). Left ventricular outflow tract velocity (P = 0.017), left ventricular ejection fraction (P = 0.018), and E:e’ ratio (P = 0.050) were associated with LS-NVE. Conclusions: Echocardiographic measurements were associated with subsequent LS-NVE development in this pilot study. A larger cohort of LS-NVE patients, however, is needed to validate these findings. |
| format | Article |
| id | doaj-art-1f684456e16c4ee2ac795ee8065dfd0f |
| institution | Kabale University |
| issn | 2994-5526 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Open Exploration Publishing Inc. |
| record_format | Article |
| series | Exploration of Cardiology |
| spelling | doaj-art-1f684456e16c4ee2ac795ee8065dfd0f2025-08-20T03:50:31ZengOpen Exploration Publishing Inc.Exploration of Cardiology2994-55262024-09-012520421610.37349/ec.2024.00034Echocardiographic findings and subsequent risk of native valve endocarditisJuan A. Quintero-Martinez0https://orcid.org/0000-0002-0785-9868Joya-Rita Hindy1Hector R. Villarraga2Brian D. Lahr3Mark J. Dayer4Martin H. Thornhill5https://orcid.org/0000-0003-0681-4083John C. O’Horo6Hector I. Michelena7Nandan S. Anavekar8Parham Sendi9Daniel C. DeSimone10Larry M. Baddour11https://orcid.org/0000-0002-4473-7077Division of Public Health, Infectious Diseases and Occupational Health, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Cardiovascular Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Internal Medicine, University of Miami Miller School of Medicine/Jackson Memorial Hospital, Miami, FL 33136, USADivision of Public Health, Infectious Diseases and Occupational Health, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USADepartment of Cardiovascular Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USADivision of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USADepartment of Cardiology, Somerset NHS Foundation Trust, TA1 5DA Taunton, UKDepartment of Oral and Maxillofacial Medicine, School of Clinical Dentistry, The University of Sheffield Faculty of Medicine, Dentistry and Health, S10 2TA Sheffield, UKDivision of Public Health, Infectious Diseases and Occupational Health, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USADepartment of Cardiovascular Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USADepartment of Cardiovascular Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USAInstitute for Infectious Diseases, University of Bern, 3001 Bern, SwitzerlandDivision of Public Health, Infectious Diseases and Occupational Health, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Cardiovascular Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USADivision of Public Health, Infectious Diseases and Occupational Health, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USA; Department of Cardiovascular Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN 55905, USAAim: The association of echocardiographic findings and subsequent risk of left-sided native valve endocarditis (LS-NVE) is undefined. The aim of this study was to determine if transthoracic echocardiography (TTE) measurements are associated with the subsequent development of LS-NVE in patients without cardiac predisposing conditions. Methods: Institutional databases were evaluated for adults diagnosed with LS-NVE from 2008 to 2020. Patients with prosthetic valves, cardiovascular implantable electronic devices, intracardiac devices, injection drug use, and predisposing cardiac conditions were excluded. Only patients who had a TTE performed 6 months to 3 years before the development of LS-NVE were included as cases. Controls were patients within the same Mayo location with a TTE report and were matched in a 1:3 ratio according to age, gender, Charlson comorbidity index, and echocardiography date. Results: There were 148 cases and 431 matched controls. As compared to controls, infective endocarditis (IE) cases had a higher prevalence of diabetes mellitus (46.6% vs. 30.4%) and chronic kidney disease (46.6% vs. 28.1%) (P < 0.001). Left ventricular outflow tract velocity (P = 0.017), left ventricular ejection fraction (P = 0.018), and E:e’ ratio (P = 0.050) were associated with LS-NVE. Conclusions: Echocardiographic measurements were associated with subsequent LS-NVE development in this pilot study. A larger cohort of LS-NVE patients, however, is needed to validate these findings.https://www.explorationpub.com/uploads/Article/A101234/101234.pdfendocarditisechocardiographynative valveleft-sidedmeasurementsrisk |
| spellingShingle | Juan A. Quintero-Martinez Joya-Rita Hindy Hector R. Villarraga Brian D. Lahr Mark J. Dayer Martin H. Thornhill John C. O’Horo Hector I. Michelena Nandan S. Anavekar Parham Sendi Daniel C. DeSimone Larry M. Baddour Echocardiographic findings and subsequent risk of native valve endocarditis Exploration of Cardiology endocarditis echocardiography native valve left-sided measurements risk |
| title | Echocardiographic findings and subsequent risk of native valve endocarditis |
| title_full | Echocardiographic findings and subsequent risk of native valve endocarditis |
| title_fullStr | Echocardiographic findings and subsequent risk of native valve endocarditis |
| title_full_unstemmed | Echocardiographic findings and subsequent risk of native valve endocarditis |
| title_short | Echocardiographic findings and subsequent risk of native valve endocarditis |
| title_sort | echocardiographic findings and subsequent risk of native valve endocarditis |
| topic | endocarditis echocardiography native valve left-sided measurements risk |
| url | https://www.explorationpub.com/uploads/Article/A101234/101234.pdf |
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