Respiratory presentation of patients infected with enterovirus D68 in Taiwan
Background: Enterovirus-D68 (EV-D68) has been endemic in Taiwan for some years with a small number of positive cases. Detailed information about respiratory presentation is lacking. This study characterized the clinical course in children admitted to the medical center and regional hospital in Taich...
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| Format: | Article |
| Language: | English |
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Elsevier
2020-04-01
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| Series: | Pediatrics and Neonatology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1875957219305029 |
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| author | Hui-Hsien Pan Chi-Ren Tsai Pei-Ju Ting Fang-Liang Huang Li-Chung Wang Chin-Fu Lin Jiunn-Liang Ko Ko-Huang Lue Po-Yen Chen |
| author_facet | Hui-Hsien Pan Chi-Ren Tsai Pei-Ju Ting Fang-Liang Huang Li-Chung Wang Chin-Fu Lin Jiunn-Liang Ko Ko-Huang Lue Po-Yen Chen |
| author_sort | Hui-Hsien Pan |
| collection | DOAJ |
| description | Background: Enterovirus-D68 (EV-D68) has been endemic in Taiwan for some years with a small number of positive cases. Detailed information about respiratory presentation is lacking. This study characterized the clinical course in children admitted to the medical center and regional hospital in Taichung during 2015. Methods: Retrospective chart review of patients with confirmed EV-D68 infection admitted to the medical center and regional hospital in Taichung with respiratory symptoms in the second half of 2015. Past medical history, clinical presentation, management, and course in hospital were collected and analyzed. Simple demographic data and clinical symptoms were also collected from patients confirmed with EV-D68 infection who visited clinics in Taichung. Results: Six children were included. Two patients had a prior history of asthma or recurrent dyspnea, and one had other preexisting medical comorbidities. One child was admitted to the pediatric intensive care unit. All the patients were cured. Cough, rhinorrhea, tachypnea and fever were the most common clinical symptoms among inpatients, while influenza-like illness (ILI) was prevalent in outpatients. Conclusion: EV-D68 infection resulted in respiratory presentations of asthma-like illness in the hospitalized pediatric population. Patients with a prior history of asthma or recurrent dyspnea appear to be more severely affected. Key Words: enterovirus D68, respiratory presentation, taiwan |
| format | Article |
| id | doaj-art-1f636b69901f4d4cbe979bb89dacf05a |
| institution | OA Journals |
| issn | 1875-9572 |
| language | English |
| publishDate | 2020-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj-art-1f636b69901f4d4cbe979bb89dacf05a2025-08-20T02:00:39ZengElsevierPediatrics and Neonatology1875-95722020-04-0161216817310.1016/j.pedneo.2019.09.006Respiratory presentation of patients infected with enterovirus D68 in TaiwanHui-Hsien Pan0Chi-Ren Tsai1Pei-Ju Ting2Fang-Liang Huang3Li-Chung Wang4Chin-Fu Lin5Jiunn-Liang Ko6Ko-Huang Lue7Po-Yen Chen8Department of Pediatrics, Chung-Shan Medical University Hospital, Taichung City, Taiwan; Institute of Medicine, Chung Shan Medical University, Taichung City, Taiwan; School of Medicine, Chung Shan Medical University, Taichung City, TaiwanDepartment of Pediatrics, Taichung Veterans General Hospital, Taichung City, TaiwanDepartment of Pediatrics, Taichung Veterans General Hospital, Taichung City, TaiwanDepartment of Pediatrics, Taichung Veterans General Hospital, Taichung City, Taiwan; Hung Kuang University, Taichung, TaiwanMicrobiology Section of the Medical Laboratory Department, Taichung Veterans General Hospital, Taichung, TaiwanMicrobiology Section of the Medical Laboratory Department, Taichung Veterans General Hospital, Taichung, TaiwanDepartment of Pediatrics, Chung-Shan Medical University Hospital, Taichung City, Taiwan; Institute of Medicine, Chung Shan Medical University, Taichung City, Taiwan; Department of Medical Oncology and Chest Medicine, Chung Shan Medical University Hospital, Taichung, TaiwanDepartment of Pediatrics, Chung-Shan Medical University Hospital, Taichung City, Taiwan; Institute of Medicine, Chung Shan Medical University, Taichung City, Taiwan; School of Medicine, Chung Shan Medical University, Taichung City, Taiwan; Corresponding author. Department of Pediatrics, Chung Shan Medical University Hospital; School of Medicine, Chung Shan Medical University; Institute of Medicine, Chung Shan Medical University, No. 110, Sec. 1, Jianguo N. Road, Taichung City, 40201, Taiwan.School of Medicine, Chung Shan Medical University, Taichung City, Taiwan; Department of Pediatrics, Taichung Veterans General Hospital, Taichung City, Taiwan; Corresponding author. Division of Pediatric Infectious Disease, Department of Pediatrics, Taichung Veterans General Hospital, Taichung, Taiwan, 1650 Taiwan Boulevard Sect. 4, Taichung, 40705, Taiwan.Background: Enterovirus-D68 (EV-D68) has been endemic in Taiwan for some years with a small number of positive cases. Detailed information about respiratory presentation is lacking. This study characterized the clinical course in children admitted to the medical center and regional hospital in Taichung during 2015. Methods: Retrospective chart review of patients with confirmed EV-D68 infection admitted to the medical center and regional hospital in Taichung with respiratory symptoms in the second half of 2015. Past medical history, clinical presentation, management, and course in hospital were collected and analyzed. Simple demographic data and clinical symptoms were also collected from patients confirmed with EV-D68 infection who visited clinics in Taichung. Results: Six children were included. Two patients had a prior history of asthma or recurrent dyspnea, and one had other preexisting medical comorbidities. One child was admitted to the pediatric intensive care unit. All the patients were cured. Cough, rhinorrhea, tachypnea and fever were the most common clinical symptoms among inpatients, while influenza-like illness (ILI) was prevalent in outpatients. Conclusion: EV-D68 infection resulted in respiratory presentations of asthma-like illness in the hospitalized pediatric population. Patients with a prior history of asthma or recurrent dyspnea appear to be more severely affected. Key Words: enterovirus D68, respiratory presentation, taiwanhttp://www.sciencedirect.com/science/article/pii/S1875957219305029 |
| spellingShingle | Hui-Hsien Pan Chi-Ren Tsai Pei-Ju Ting Fang-Liang Huang Li-Chung Wang Chin-Fu Lin Jiunn-Liang Ko Ko-Huang Lue Po-Yen Chen Respiratory presentation of patients infected with enterovirus D68 in Taiwan Pediatrics and Neonatology |
| title | Respiratory presentation of patients infected with enterovirus D68 in Taiwan |
| title_full | Respiratory presentation of patients infected with enterovirus D68 in Taiwan |
| title_fullStr | Respiratory presentation of patients infected with enterovirus D68 in Taiwan |
| title_full_unstemmed | Respiratory presentation of patients infected with enterovirus D68 in Taiwan |
| title_short | Respiratory presentation of patients infected with enterovirus D68 in Taiwan |
| title_sort | respiratory presentation of patients infected with enterovirus d68 in taiwan |
| url | http://www.sciencedirect.com/science/article/pii/S1875957219305029 |
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