The relationship between personality traits and health-related quality of life after mild-to-moderate traumatic brain injury

Abstract Background Traumatic brain injury (TBI) causes major societal burden and may negatively influence an individual’s health-related quality of life (HRQoL). Personality factors have been linked to persistent post-concussion symptoms (PPCS), and PPCS have been found to affect HRQoL. However, th...

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Main Authors: Benedikte Å. Madsen, Silje C. R. Fure, Cecilie Røe, Daniel Løke, Marianne Løvstad, Nada Andelic, Emilie Isager Howe
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Neurology
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Online Access:https://doi.org/10.1186/s12883-025-04153-0
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Summary:Abstract Background Traumatic brain injury (TBI) causes major societal burden and may negatively influence an individual’s health-related quality of life (HRQoL). Personality factors have been linked to persistent post-concussion symptoms (PPCS), and PPCS have been found to affect HRQoL. However, there is a knowledge gap concerning the association between personality traits and HRQoL after mild-to-moderate TBI. Thus, this study aims to investigate the association between personality traits and HRQoL in patients with mild-to-moderate TBI at 15 months post-injury, while controlling for socio-demographic characteristics, injury-related factors and symptom burden. Methods Data from 86 participants with mild- to-moderate TBI from a previous randomised controlled trial were analysed. Sociodemographic, injury-related and psychological factors were recorded 2–3 months post-injury. Personality traits were measured at 15 months post-injury with The NEO Five-factor Inventory-3. The Quality of Life after Brain Injury– Overall Scale (QOLIBRI-OS) and the EuroQol-visual analogue scale (EQ-VAS) were used to measure HRQoL at 15 months post-injury. Two separate multiple linear regression models were performed for the outcome variables; QOLIBRI-OS (model 1) and EQ-VAS (model 2). Results The factors associated with lower HRQoL were more severe PPCS, higher levels of the personality traits neuroticism and conscientiousness (model 1), female sex and being single/living alone (model 2). Higher levels of the personality trait extraversion were associated with higher HRQoL in both models. Conclusion The results highlight how non-injury factors may be associated with recovery and HRQoL after TBI. Considering personality factors may be helpful when identifying individual risk and protective factors for outcomes after mild-to-moderate TBI.
ISSN:1471-2377