Insights into the Anti-inflammatory and Antiviral Mechanisms of Resveratrol
Resveratrol is a naturally occurring stilbene phytoalexin phenolic compound, which has been extensively studied on its biological activity. It has been widely accepted that resveratrol possesses anti-inflammatory and antiviral activities. In this review, we summarize the anti-inflammatory dosages an...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2022/7138756 |
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| _version_ | 1849307965074440192 |
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| author | Xiangxiu Chen Xu Song Xinghong Zhao Yu Zhang Yiming Wang Renyong Jia Yuanfeng Zou Lixia Li Zhongqiong Yin |
| author_facet | Xiangxiu Chen Xu Song Xinghong Zhao Yu Zhang Yiming Wang Renyong Jia Yuanfeng Zou Lixia Li Zhongqiong Yin |
| author_sort | Xiangxiu Chen |
| collection | DOAJ |
| description | Resveratrol is a naturally occurring stilbene phytoalexin phenolic compound, which has been extensively studied on its biological activity. It has been widely accepted that resveratrol possesses anti-inflammatory and antiviral activities. In this review, we summarize the anti-inflammatory dosages and mechanism and antiviral mechanism of resveratrol. Since viral infections are often accompanied by inflammation, we propose that the NF-κB signaling pathway is a key and common molecular mechanism of resveratrol to exert anti-inflammatory and antiviral effects. For future studies, we believe that resveratrol’s anti-inflammatory and antiviral mechanisms can consider the upstream signaling molecules of the NF-κB signaling pathway. For resveratrol antivirus, future studies can be conducted on the interaction of resveratrol with key proteins or important enzymes of the virus. In addition, we also think that the clinical application of resveratrol is very important. In short, resveratrol is a promising anti-inflammatory and antiviral drug, and research on it needs to be expanded. |
| format | Article |
| id | doaj-art-1f4837dcb4bc4862801a491f94ada850 |
| institution | Kabale University |
| issn | 1466-1861 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-1f4837dcb4bc4862801a491f94ada8502025-08-20T03:54:36ZengWileyMediators of Inflammation1466-18612022-01-01202210.1155/2022/7138756Insights into the Anti-inflammatory and Antiviral Mechanisms of ResveratrolXiangxiu Chen0Xu Song1Xinghong Zhao2Yu Zhang3Yiming Wang4Renyong Jia5Yuanfeng Zou6Lixia Li7Zhongqiong Yin8Natural Medicine Research CenterNatural Medicine Research CenterNatural Medicine Research CenterNatural Medicine Research CenterNatural Medicine Research CenterKey Laboratory of Animal Disease and Human Health of Sichuan ProvinceNatural Medicine Research CenterNatural Medicine Research CenterNatural Medicine Research CenterResveratrol is a naturally occurring stilbene phytoalexin phenolic compound, which has been extensively studied on its biological activity. It has been widely accepted that resveratrol possesses anti-inflammatory and antiviral activities. In this review, we summarize the anti-inflammatory dosages and mechanism and antiviral mechanism of resveratrol. Since viral infections are often accompanied by inflammation, we propose that the NF-κB signaling pathway is a key and common molecular mechanism of resveratrol to exert anti-inflammatory and antiviral effects. For future studies, we believe that resveratrol’s anti-inflammatory and antiviral mechanisms can consider the upstream signaling molecules of the NF-κB signaling pathway. For resveratrol antivirus, future studies can be conducted on the interaction of resveratrol with key proteins or important enzymes of the virus. In addition, we also think that the clinical application of resveratrol is very important. In short, resveratrol is a promising anti-inflammatory and antiviral drug, and research on it needs to be expanded.http://dx.doi.org/10.1155/2022/7138756 |
| spellingShingle | Xiangxiu Chen Xu Song Xinghong Zhao Yu Zhang Yiming Wang Renyong Jia Yuanfeng Zou Lixia Li Zhongqiong Yin Insights into the Anti-inflammatory and Antiviral Mechanisms of Resveratrol Mediators of Inflammation |
| title | Insights into the Anti-inflammatory and Antiviral Mechanisms of Resveratrol |
| title_full | Insights into the Anti-inflammatory and Antiviral Mechanisms of Resveratrol |
| title_fullStr | Insights into the Anti-inflammatory and Antiviral Mechanisms of Resveratrol |
| title_full_unstemmed | Insights into the Anti-inflammatory and Antiviral Mechanisms of Resveratrol |
| title_short | Insights into the Anti-inflammatory and Antiviral Mechanisms of Resveratrol |
| title_sort | insights into the anti inflammatory and antiviral mechanisms of resveratrol |
| url | http://dx.doi.org/10.1155/2022/7138756 |
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