Six Cases of Polypoidal Choroidal Vasculopathy in Eyes with Choroidal Nevi

Introduction: The aim of this study was to report the cases of 6 patients with the coexistence of polypoidal choroidal vasculopathy (PCV) and choroidal nevi. Case Presentation: Six patients with the coexistence of PCV and choroidal nevi were thoroughly evaluated by slit-lamp biomicroscopy...

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Main Authors: Andrea Gaggino, Leandro Inferrera, Serena Milan, Marianna Presotto, Daniele Tognetto
Format: Article
Language:English
Published: Karger Publishers 2025-02-01
Series:Case Reports in Ophthalmology
Online Access:https://karger.com/article/doi/10.1159/000543643
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author Andrea Gaggino
Leandro Inferrera
Serena Milan
Marianna Presotto
Daniele Tognetto
author_facet Andrea Gaggino
Leandro Inferrera
Serena Milan
Marianna Presotto
Daniele Tognetto
author_sort Andrea Gaggino
collection DOAJ
description Introduction: The aim of this study was to report the cases of 6 patients with the coexistence of polypoidal choroidal vasculopathy (PCV) and choroidal nevi. Case Presentation: Six patients with the coexistence of PCV and choroidal nevi were thoroughly evaluated by slit-lamp biomicroscopy examination, color fundus photography, optical coherence tomography (OCT), OCT angiography (OCT-A), fluorescein angiography (FA), indocyanine green angiography (ICG-A), fundus blue autofluorescence (BAF), and ocular ultrasound (OU). The typical features of PCV and nevi were present in all patients, three of whom were treated with intravitreal anti-angiogenic agents. In each clinical case, the choroidal Haller’s vessels adjacent to the nevus were visibly more dilated compared to normal. Color fundus photography, OCT, OCT-A, FA, ICG-A, BAF, and OU revealed similar findings across all cases. Observations revealed that choroidal nevi could instigate modifications in the outer retina, resulting in persistent alterations capable of triggering the formation of neovascularization. Conclusion: The occurrence of a PCV alongside nevus is an uncommon complication. Findings from all exams performed were consistent across all cases, highlighting the potential link between PCV and nevi.
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spelling doaj-art-1f40abb77f4b428ba59cf62a0cfa67f72025-08-20T02:31:55ZengKarger PublishersCase Reports in Ophthalmology1663-26992025-02-0116118219310.1159/000543643Six Cases of Polypoidal Choroidal Vasculopathy in Eyes with Choroidal NeviAndrea GagginoLeandro InferreraSerena MilanMarianna PresottoDaniele Tognetto Introduction: The aim of this study was to report the cases of 6 patients with the coexistence of polypoidal choroidal vasculopathy (PCV) and choroidal nevi. Case Presentation: Six patients with the coexistence of PCV and choroidal nevi were thoroughly evaluated by slit-lamp biomicroscopy examination, color fundus photography, optical coherence tomography (OCT), OCT angiography (OCT-A), fluorescein angiography (FA), indocyanine green angiography (ICG-A), fundus blue autofluorescence (BAF), and ocular ultrasound (OU). The typical features of PCV and nevi were present in all patients, three of whom were treated with intravitreal anti-angiogenic agents. In each clinical case, the choroidal Haller’s vessels adjacent to the nevus were visibly more dilated compared to normal. Color fundus photography, OCT, OCT-A, FA, ICG-A, BAF, and OU revealed similar findings across all cases. Observations revealed that choroidal nevi could instigate modifications in the outer retina, resulting in persistent alterations capable of triggering the formation of neovascularization. Conclusion: The occurrence of a PCV alongside nevus is an uncommon complication. Findings from all exams performed were consistent across all cases, highlighting the potential link between PCV and nevi. https://karger.com/article/doi/10.1159/000543643
spellingShingle Andrea Gaggino
Leandro Inferrera
Serena Milan
Marianna Presotto
Daniele Tognetto
Six Cases of Polypoidal Choroidal Vasculopathy in Eyes with Choroidal Nevi
Case Reports in Ophthalmology
title Six Cases of Polypoidal Choroidal Vasculopathy in Eyes with Choroidal Nevi
title_full Six Cases of Polypoidal Choroidal Vasculopathy in Eyes with Choroidal Nevi
title_fullStr Six Cases of Polypoidal Choroidal Vasculopathy in Eyes with Choroidal Nevi
title_full_unstemmed Six Cases of Polypoidal Choroidal Vasculopathy in Eyes with Choroidal Nevi
title_short Six Cases of Polypoidal Choroidal Vasculopathy in Eyes with Choroidal Nevi
title_sort six cases of polypoidal choroidal vasculopathy in eyes with choroidal nevi
url https://karger.com/article/doi/10.1159/000543643
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