The Application of Biologically Active Components Derived from Mineral, Synthetic, Phyto- and Organic Sources for Developing Local Hemostatic Agents: Historical Traditions and Contemporary Advancements
The present paper aims to provide an overview of the use of biologically active components derived from mineral, synthetic, phyto-, and organic sources in the development of local hemostatic agents. The study highlights the historical and contemporary use of these agents in medical practice, and ex...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Kazimierz Wielki University
2025-01-01
|
| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/57568 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841556476995305472 |
|---|---|
| author | S. Abramov S. Sokolovskyi A. Gozhenko I. Sobko G. Titov V. Gladyshev M. Khmil Ugis Kletnieks |
| author_facet | S. Abramov S. Sokolovskyi A. Gozhenko I. Sobko G. Titov V. Gladyshev M. Khmil Ugis Kletnieks |
| author_sort | S. Abramov |
| collection | DOAJ |
| description |
The present paper aims to provide an overview of the use of biologically active components derived from mineral, synthetic, phyto-, and organic sources in the development of local hemostatic agents. The study highlights the historical and contemporary use of these agents in medical practice, and examines the scientific evidence supporting their efficacy.
Hemostasis, the process of stopping bleeding, is a critical component of surgical and medical procedures. Local hemostatic agents are widely used to achieve hemostasis in a targeted and controlled manner, thereby minimizing the risk of complications associated with bleeding.
The use of biologically active components derived from various sources, including minerals, synthetic materials, plants, and organic compounds, has a long history in the development of hemostatic agents. These components can act through various mechanisms, such as inducing platelet aggregation, activating the coagulation cascade, or promoting the formation of blood clots.
Recent advances in biotechnology and nanotechnology have led to the development of novel hemostatic agents with improved properties, such as enhanced biocompatibility, targeted delivery, and controlled release. These agents have the potential to revolutionize hemostasis in surgical and medical procedures, and improve patient outcomes.
Overall, the study highlights the importance of biologically active components derived from mineral, synthetic, phyto-, and organic sources in the development of local hemostatic agents. The review of historical and contemporary use of these agents underscores their continued relevance in medical practice, while recent advances in technology offer exciting new possibilities for future development.
After a thorough review of domestic and foreign literature, the development team used adsorbing materials from biologically active components of mineral, synthetic, phyto-, and organic origin to create a hemostatic powder known as "PLANTOR." The active components of PLANTOR include aerosol, carrageenan of a special brand, and a specific mixture of medicinal vegetable oils, which have a special sorption effect. Due to the well-selected composition of the product, PLANTOR forms a blood clot in the wound through a biophysical process of liquid absorption. Notably, PLANTOR does not contain procoagulant minerals or nanoparticles that could remain in the human body, and therefore does not belong to means with a chemical or biochemical mechanism of action.
Based on the above, it is possible to recommend the hemostatic agent-powder "PLANTOR" of the trade mark "PLANTOR tm" and "Dr. Sokolovskiy R" of the manufacturer "Medpro Nutraceuticals" (Latvia) by order of LLC "Plantor" (Ukraine, Dnipro), the author and owner of the developed technology of the hemostatic agent - powder "PLANTOR" (TU U 20.4-44827581-001:2022) as an auxiliary means of revitalization, local coagulation, treated wound surfaces during emergency medical care for external bleeding.
|
| format | Article |
| id | doaj-art-1f3b6b30ad5f435bba45aad3fbab9ba3 |
| institution | Kabale University |
| issn | 2391-8306 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj-art-1f3b6b30ad5f435bba45aad3fbab9ba32025-01-07T08:16:38ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062025-01-017510.12775/JEHS.2024.75.57568The Application of Biologically Active Components Derived from Mineral, Synthetic, Phyto- and Organic Sources for Developing Local Hemostatic Agents: Historical Traditions and Contemporary AdvancementsS. Abramov0S. Sokolovskyi1A. Gozhenko2I. Sobko3G. Titov4V. Gladyshev5M. Khmil6Ugis Kletnieks7Dnipro Medical Institute of Traditional and Non-Traditional MedicineDnipro Medical Institute of Traditional and Non-Traditional MedicineState Enterprise Ukrainian Research Institute of Transport Medicine Ukrainian Military Medical Academy of the Ministry of Defense of UkraineDnipro Medical Institute of Traditional and Non-Traditional MedicineZaporozhye State Medical UniversityOfficial Representative Office in Ukraine of the International Nobel Information CentreLatvian Longevity Association The present paper aims to provide an overview of the use of biologically active components derived from mineral, synthetic, phyto-, and organic sources in the development of local hemostatic agents. The study highlights the historical and contemporary use of these agents in medical practice, and examines the scientific evidence supporting their efficacy. Hemostasis, the process of stopping bleeding, is a critical component of surgical and medical procedures. Local hemostatic agents are widely used to achieve hemostasis in a targeted and controlled manner, thereby minimizing the risk of complications associated with bleeding. The use of biologically active components derived from various sources, including minerals, synthetic materials, plants, and organic compounds, has a long history in the development of hemostatic agents. These components can act through various mechanisms, such as inducing platelet aggregation, activating the coagulation cascade, or promoting the formation of blood clots. Recent advances in biotechnology and nanotechnology have led to the development of novel hemostatic agents with improved properties, such as enhanced biocompatibility, targeted delivery, and controlled release. These agents have the potential to revolutionize hemostasis in surgical and medical procedures, and improve patient outcomes. Overall, the study highlights the importance of biologically active components derived from mineral, synthetic, phyto-, and organic sources in the development of local hemostatic agents. The review of historical and contemporary use of these agents underscores their continued relevance in medical practice, while recent advances in technology offer exciting new possibilities for future development. After a thorough review of domestic and foreign literature, the development team used adsorbing materials from biologically active components of mineral, synthetic, phyto-, and organic origin to create a hemostatic powder known as "PLANTOR." The active components of PLANTOR include aerosol, carrageenan of a special brand, and a specific mixture of medicinal vegetable oils, which have a special sorption effect. Due to the well-selected composition of the product, PLANTOR forms a blood clot in the wound through a biophysical process of liquid absorption. Notably, PLANTOR does not contain procoagulant minerals or nanoparticles that could remain in the human body, and therefore does not belong to means with a chemical or biochemical mechanism of action. Based on the above, it is possible to recommend the hemostatic agent-powder "PLANTOR" of the trade mark "PLANTOR tm" and "Dr. Sokolovskiy R" of the manufacturer "Medpro Nutraceuticals" (Latvia) by order of LLC "Plantor" (Ukraine, Dnipro), the author and owner of the developed technology of the hemostatic agent - powder "PLANTOR" (TU U 20.4-44827581-001:2022) as an auxiliary means of revitalization, local coagulation, treated wound surfaces during emergency medical care for external bleeding. https://apcz.umk.pl/JEHS/article/view/57568bleedinghemostatic agentsadsorbing materialsnatural hemostatics |
| spellingShingle | S. Abramov S. Sokolovskyi A. Gozhenko I. Sobko G. Titov V. Gladyshev M. Khmil Ugis Kletnieks The Application of Biologically Active Components Derived from Mineral, Synthetic, Phyto- and Organic Sources for Developing Local Hemostatic Agents: Historical Traditions and Contemporary Advancements Journal of Education, Health and Sport bleeding hemostatic agents adsorbing materials natural hemostatics |
| title | The Application of Biologically Active Components Derived from Mineral, Synthetic, Phyto- and Organic Sources for Developing Local Hemostatic Agents: Historical Traditions and Contemporary Advancements |
| title_full | The Application of Biologically Active Components Derived from Mineral, Synthetic, Phyto- and Organic Sources for Developing Local Hemostatic Agents: Historical Traditions and Contemporary Advancements |
| title_fullStr | The Application of Biologically Active Components Derived from Mineral, Synthetic, Phyto- and Organic Sources for Developing Local Hemostatic Agents: Historical Traditions and Contemporary Advancements |
| title_full_unstemmed | The Application of Biologically Active Components Derived from Mineral, Synthetic, Phyto- and Organic Sources for Developing Local Hemostatic Agents: Historical Traditions and Contemporary Advancements |
| title_short | The Application of Biologically Active Components Derived from Mineral, Synthetic, Phyto- and Organic Sources for Developing Local Hemostatic Agents: Historical Traditions and Contemporary Advancements |
| title_sort | application of biologically active components derived from mineral synthetic phyto and organic sources for developing local hemostatic agents historical traditions and contemporary advancements |
| topic | bleeding hemostatic agents adsorbing materials natural hemostatics |
| url | https://apcz.umk.pl/JEHS/article/view/57568 |
| work_keys_str_mv | AT sabramov theapplicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT ssokolovskyi theapplicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT agozhenko theapplicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT isobko theapplicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT gtitov theapplicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT vgladyshev theapplicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT mkhmil theapplicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT ugiskletnieks theapplicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT sabramov applicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT ssokolovskyi applicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT agozhenko applicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT isobko applicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT gtitov applicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT vgladyshev applicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT mkhmil applicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements AT ugiskletnieks applicationofbiologicallyactivecomponentsderivedfrommineralsyntheticphytoandorganicsourcesfordevelopinglocalhemostaticagentshistoricaltraditionsandcontemporaryadvancements |