The intervention effect of long-term exercise on depression and anxiety in college students: a three-level meta-analysis

Abstract Background Mental health issues, especially depression and anxiety, are prevalent among college students. Long-term exercise has been shown to improve depression and anxiety in college students. Therefore, this study aims to systematically and comprehensively evaluate the intervention effec...

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Main Authors: Jun Li, Ling Zhang, Fan Yu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Psychology
Subjects:
Online Access:https://doi.org/10.1186/s40359-025-03009-z
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author Jun Li
Ling Zhang
Fan Yu
author_facet Jun Li
Ling Zhang
Fan Yu
author_sort Jun Li
collection DOAJ
description Abstract Background Mental health issues, especially depression and anxiety, are prevalent among college students. Long-term exercise has been shown to improve depression and anxiety in college students. Therefore, this study aims to systematically and comprehensively evaluate the intervention effect of long-term exercise on depression and anxiety in college students using a three-level meta-analysis. Methods A computer-based search was conducted in five databases—China National Knowledge Infrastructure (CNKI), PubMed, Embase, The Cochrane Library, and Web of Science—for randomized controlled trials (RCTs) investigating the effects of long-term exercise interventions on depression and anxiety in college students. The search covered all records from the inception of each database up to January 11, 2025. The quality of the included studies was assessed using the PEDro scale, and the evidence quality was evaluated using GRADEpro. A three-level meta-analysis with a random-effects model was performed using the metafor package in R 4.3.0. Results In total, 36 studies were included in this meta-analysis. Long-term exercise significantly improved depression (g = -0.89, 95% CI [-1.23, -0.54], p < 0.001) and anxiety (g = -0.64, 95% CI [-0.96, -0.32], p < 0.001) in college students. Exercise type, time, frequency, cycle, and questionnaire type were not found to be moderators (all p > 0.05). The evidence quality, as assessed by GRADEpro, was rated as high. Conclusion Long-term exercise can improve depression and anxiety in college students. However, future studies should use more rigorous methodologies and explore the intervention effects of various exercise parameters on depression and anxiety in this population.
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spelling doaj-art-1f3a4757e7e347539f87870dcfb7d19e2025-08-20T04:01:42ZengBMCBMC Psychology2050-72832025-07-0113112010.1186/s40359-025-03009-zThe intervention effect of long-term exercise on depression and anxiety in college students: a three-level meta-analysisJun Li0Ling Zhang1Fan Yu2School of Sport Management, Shandong Sport UniversitySchool of Sport Communication and Information Technology, Shandong Sport UniversityInstitute of Vocational Higher Education, Shandong PolytechnicAbstract Background Mental health issues, especially depression and anxiety, are prevalent among college students. Long-term exercise has been shown to improve depression and anxiety in college students. Therefore, this study aims to systematically and comprehensively evaluate the intervention effect of long-term exercise on depression and anxiety in college students using a three-level meta-analysis. Methods A computer-based search was conducted in five databases—China National Knowledge Infrastructure (CNKI), PubMed, Embase, The Cochrane Library, and Web of Science—for randomized controlled trials (RCTs) investigating the effects of long-term exercise interventions on depression and anxiety in college students. The search covered all records from the inception of each database up to January 11, 2025. The quality of the included studies was assessed using the PEDro scale, and the evidence quality was evaluated using GRADEpro. A three-level meta-analysis with a random-effects model was performed using the metafor package in R 4.3.0. Results In total, 36 studies were included in this meta-analysis. Long-term exercise significantly improved depression (g = -0.89, 95% CI [-1.23, -0.54], p < 0.001) and anxiety (g = -0.64, 95% CI [-0.96, -0.32], p < 0.001) in college students. Exercise type, time, frequency, cycle, and questionnaire type were not found to be moderators (all p > 0.05). The evidence quality, as assessed by GRADEpro, was rated as high. Conclusion Long-term exercise can improve depression and anxiety in college students. However, future studies should use more rigorous methodologies and explore the intervention effects of various exercise parameters on depression and anxiety in this population.https://doi.org/10.1186/s40359-025-03009-zLong-term exerciseCollege studentsDepressionAnxietyMeta-analysis
spellingShingle Jun Li
Ling Zhang
Fan Yu
The intervention effect of long-term exercise on depression and anxiety in college students: a three-level meta-analysis
BMC Psychology
Long-term exercise
College students
Depression
Anxiety
Meta-analysis
title The intervention effect of long-term exercise on depression and anxiety in college students: a three-level meta-analysis
title_full The intervention effect of long-term exercise on depression and anxiety in college students: a three-level meta-analysis
title_fullStr The intervention effect of long-term exercise on depression and anxiety in college students: a three-level meta-analysis
title_full_unstemmed The intervention effect of long-term exercise on depression and anxiety in college students: a three-level meta-analysis
title_short The intervention effect of long-term exercise on depression and anxiety in college students: a three-level meta-analysis
title_sort intervention effect of long term exercise on depression and anxiety in college students a three level meta analysis
topic Long-term exercise
College students
Depression
Anxiety
Meta-analysis
url https://doi.org/10.1186/s40359-025-03009-z
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