Posterior reversible encephalopathy syndrome with reversible cerebral vasoconstriction syndrome in a normal primigravida woman at the 35-week gestational stage: a case report

Background: Herein, we report a case of cerebral hemorrhage in a 21-year-old nulliparous, primi gravida woman caused by posterior reversible encephalopathy syndrome (PRES), which may be associated with reversible cerebral vasoconstriction syndrome (RCVS). Case: The patient’s medical history was unre...

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Main Authors: Shingo Tanaka, Maki Goto, Saya Watanabe, Sachino Kira, Sotaro Hayashi, Shigeki Fujimoto, Miho Oda, Lifa Lee, Yoko To, Satoshi Nishiyama, Fuyuki Eguchi, Hiroshi Tsujioka
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Language:English
Published: IMR Press 2021-08-01
Series:Clinical and Experimental Obstetrics & Gynecology
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Online Access:https://www.imrpress.com/journal/CEOG/48/4/10.31083/j.ceog4804156
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author Shingo Tanaka
Maki Goto
Saya Watanabe
Sachino Kira
Sotaro Hayashi
Shigeki Fujimoto
Miho Oda
Lifa Lee
Yoko To
Satoshi Nishiyama
Fuyuki Eguchi
Hiroshi Tsujioka
author_facet Shingo Tanaka
Maki Goto
Saya Watanabe
Sachino Kira
Sotaro Hayashi
Shigeki Fujimoto
Miho Oda
Lifa Lee
Yoko To
Satoshi Nishiyama
Fuyuki Eguchi
Hiroshi Tsujioka
author_sort Shingo Tanaka
collection DOAJ
description Background: Herein, we report a case of cerebral hemorrhage in a 21-year-old nulliparous, primi gravida woman caused by posterior reversible encephalopathy syndrome (PRES), which may be associated with reversible cerebral vasoconstriction syndrome (RCVS). Case: The patient’s medical history was unremarkable, apart from the mother having had a cerebral infarction. She had been examined by a local doctor, and showed good progress; however, her blood pressure (BP) was 143/97 mmHg, she had findings of proteinuria (3+) and she had a headache on the 35th week with multiple vomiting episodes. She was admitted to our hospital after poor responsiveness and a consciousness level of GCS14, E4V4M6, a BP of 143/97 mmHg, a pulse rate of 77/min, bilateral abduction of the eyes, and left hemiplegia. Cranial computed tomography (CT) revealed cerebral hemorrhage with ventricular puncture in the right caudate nucleus. Emergency caesarean section was performed on the same day with priority given to maternal lifesaving. Acute cerebral infarction findings and PRES were observed on head magnetic resonance imaging (MRI) on the admission day 1. Head MR angiography on the 4th hospital day showed narrowing of the entire main artery trunk, suspected as RCVS. Short-term memory deficits were diagnosed post-extubation, but gradually improved. Although it became possible and hematoma in the ventricles were absorbed, left paresis and higher dysfunction were observed, and she was discharged on the 21st hospital day. Conclusion: PRES and RCVS occur simultaneously quite frequently, but require opposing treatment approaches. Both cases are reversible, but if they occur simultaneously, RCVS, which progresses slowly, may cause irreversible symptoms, thereby requiring careful treatment.
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spelling doaj-art-1f394899632e4d41bcfefe0484d452ae2025-08-20T02:04:34ZengIMR PressClinical and Experimental Obstetrics & Gynecology0390-66632021-08-0148498298610.31083/j.ceog4804156S0390-6663(21)00177-9Posterior reversible encephalopathy syndrome with reversible cerebral vasoconstriction syndrome in a normal primigravida woman at the 35-week gestational stage: a case reportShingo Tanaka0Maki Goto1Saya Watanabe2Sachino Kira3Sotaro Hayashi4Shigeki Fujimoto5Miho Oda6Lifa Lee7Yoko To8Satoshi Nishiyama9Fuyuki Eguchi10Hiroshi Tsujioka11Iizuka Hospital Obstetrics and Gynecology, Yoshiomachi, 3-83 iizukashi, Fukuokakenn, JapanIizuka Hospital Obstetrics and Gynecology, Yoshiomachi, 3-83 iizukashi, Fukuokakenn, JapanIizuka Hospital Obstetrics and Gynecology, Yoshiomachi, 3-83 iizukashi, Fukuokakenn, JapanIizuka Hospital Obstetrics and Gynecology, Yoshiomachi, 3-83 iizukashi, Fukuokakenn, JapanIizuka Hospital Obstetrics and Gynecology, Yoshiomachi, 3-83 iizukashi, Fukuokakenn, JapanIizuka Hospital Obstetrics and Gynecology, Yoshiomachi, 3-83 iizukashi, Fukuokakenn, JapanIizuka Hospital Obstetrics and Gynecology, Yoshiomachi, 3-83 iizukashi, Fukuokakenn, JapanIizuka Hospital Obstetrics and Gynecology, Yoshiomachi, 3-83 iizukashi, Fukuokakenn, JapanIizuka Hospital Obstetrics and Gynecology, Yoshiomachi, 3-83 iizukashi, Fukuokakenn, JapanIizuka Hospital Obstetrics and Gynecology, Yoshiomachi, 3-83 iizukashi, Fukuokakenn, JapanIizuka Hospital Obstetrics and Gynecology, Yoshiomachi, 3-83 iizukashi, Fukuokakenn, JapanIizuka Hospital Obstetrics and Gynecology, Yoshiomachi, 3-83 iizukashi, Fukuokakenn, JapanBackground: Herein, we report a case of cerebral hemorrhage in a 21-year-old nulliparous, primi gravida woman caused by posterior reversible encephalopathy syndrome (PRES), which may be associated with reversible cerebral vasoconstriction syndrome (RCVS). Case: The patient’s medical history was unremarkable, apart from the mother having had a cerebral infarction. She had been examined by a local doctor, and showed good progress; however, her blood pressure (BP) was 143/97 mmHg, she had findings of proteinuria (3+) and she had a headache on the 35th week with multiple vomiting episodes. She was admitted to our hospital after poor responsiveness and a consciousness level of GCS14, E4V4M6, a BP of 143/97 mmHg, a pulse rate of 77/min, bilateral abduction of the eyes, and left hemiplegia. Cranial computed tomography (CT) revealed cerebral hemorrhage with ventricular puncture in the right caudate nucleus. Emergency caesarean section was performed on the same day with priority given to maternal lifesaving. Acute cerebral infarction findings and PRES were observed on head magnetic resonance imaging (MRI) on the admission day 1. Head MR angiography on the 4th hospital day showed narrowing of the entire main artery trunk, suspected as RCVS. Short-term memory deficits were diagnosed post-extubation, but gradually improved. Although it became possible and hematoma in the ventricles were absorbed, left paresis and higher dysfunction were observed, and she was discharged on the 21st hospital day. Conclusion: PRES and RCVS occur simultaneously quite frequently, but require opposing treatment approaches. Both cases are reversible, but if they occur simultaneously, RCVS, which progresses slowly, may cause irreversible symptoms, thereby requiring careful treatment.https://www.imrpress.com/journal/CEOG/48/4/10.31083/j.ceog4804156preeclampsiahypertensive crisisleft hemiplegiaposterior reversible encephalopathy syndromereversible cerebral vasoconstriction syndrome
spellingShingle Shingo Tanaka
Maki Goto
Saya Watanabe
Sachino Kira
Sotaro Hayashi
Shigeki Fujimoto
Miho Oda
Lifa Lee
Yoko To
Satoshi Nishiyama
Fuyuki Eguchi
Hiroshi Tsujioka
Posterior reversible encephalopathy syndrome with reversible cerebral vasoconstriction syndrome in a normal primigravida woman at the 35-week gestational stage: a case report
Clinical and Experimental Obstetrics & Gynecology
preeclampsia
hypertensive crisis
left hemiplegia
posterior reversible encephalopathy syndrome
reversible cerebral vasoconstriction syndrome
title Posterior reversible encephalopathy syndrome with reversible cerebral vasoconstriction syndrome in a normal primigravida woman at the 35-week gestational stage: a case report
title_full Posterior reversible encephalopathy syndrome with reversible cerebral vasoconstriction syndrome in a normal primigravida woman at the 35-week gestational stage: a case report
title_fullStr Posterior reversible encephalopathy syndrome with reversible cerebral vasoconstriction syndrome in a normal primigravida woman at the 35-week gestational stage: a case report
title_full_unstemmed Posterior reversible encephalopathy syndrome with reversible cerebral vasoconstriction syndrome in a normal primigravida woman at the 35-week gestational stage: a case report
title_short Posterior reversible encephalopathy syndrome with reversible cerebral vasoconstriction syndrome in a normal primigravida woman at the 35-week gestational stage: a case report
title_sort posterior reversible encephalopathy syndrome with reversible cerebral vasoconstriction syndrome in a normal primigravida woman at the 35 week gestational stage a case report
topic preeclampsia
hypertensive crisis
left hemiplegia
posterior reversible encephalopathy syndrome
reversible cerebral vasoconstriction syndrome
url https://www.imrpress.com/journal/CEOG/48/4/10.31083/j.ceog4804156
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