PECULIARITIES OF SECONDARY METABOLITES BIOSYNTHESIS IN PLANT CELL CULTURES

<p>metabolites formation in plant cell cultures of <em>Panax spp.,</em> (ginsenosides); <em>Dioscorea deltoidea</em> (steroid glycosides); <em>Ajuga</em> <em>reptans, Serratula coronata, Rhaponticum carthamoides </em>(ecdisteroids<em>); Pol...

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Bibliographic Details
Main Author: A.M. NOSOV
Format: Article
Language:English
Published: izzet kara 2014-06-01
Series:International Journal of Secondary Metabolite
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Online Access:http://ijate.net/index.php/ijsm/article/view/13
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Summary:<p>metabolites formation in plant cell cultures of <em>Panax spp.,</em> (ginsenosides); <em>Dioscorea deltoidea</em> (steroid glycosides); <em>Ajuga</em> <em>reptans, Serratula coronata, Rhaponticum carthamoides </em>(ecdisteroids<em>); Polyscias spp.,</em> (triterpene glycosides), <em>Taxus s</em>pp. (taxoids), <em>Stevia rebaudiana</em> (diterpene steviol-glycosides), <em>Stephania glabra</em> (alkaloids). They are some regular trends of secondary metabolites synthesis in the plant cell culture:</p><p>It can be noted the stable synthesis of the compound promoting cell proliferation. Indeed, cell cultures of <em>Dioscorea deltoidea</em> were demonstrated to accumulate only furostanol glycosides, which promoted cell division. Furostanol glycoside content of <em>Dioscorea</em> strain DM-0.5 was up to 6 - 12% by dry biomass.</p><p><em>Panax ginseng </em>and<em> P. japonicus</em> plant cell cultures synthesize as minimum seven triterpene glycosides (ginsenosides), the productivity of these compounds was up to 6.0 - 8.0% on dry biomass.</p><p>By contrast, the detectable synthesis of diterpene steviol-glycosides in cultivated cells of <em>Stevia rebaudiana</em> initiated in the mixotrophic cultures during chloroplast formation only.</p><p>Despite these differences, or mainly due to them, plant cell cultures have become an attractive source of phytochemicals in alternative to collecting wild plants. It provides a guideline to bioreactor-based production of isoprenoids using undifferentiated plant cell cultures. </p>
ISSN:2148-6905