Domain acquisition enabled functional expansion of the TFIIS transcription factor family

Abstract TFIIS and its homologs were long considered a delimited family of transcription factors, for the ability to induce RNA Polymerase II backtracking and nascent RNA cleavage. Recent studies however show that the relevant domains, which correspond to the TFIIS middle and carboxyterminal regions...

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Bibliographic Details
Main Authors: Kateryna Matveyeva, Ainhoa Sánchez de Diego, María Ángeles García-López, Julio Gutiérrez, Thierry Fischer, Karel H.M. van Wely
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cell & Bioscience
Online Access:https://doi.org/10.1186/s13578-025-01423-9
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