Human saliva exerts strong type-dependent effects on adenovirus infectivity

Human saliva exerts strong type-dependent effects on adenovirus infectivity

BackgroundThe development of mucosal adenovirus (Ad) vaccine vectors is considered one of the next frontiers to protect vulnerable patients from respiratory and gastrointestinal pathogens. An efficient delivery to or through the oral cavity necessitates a thorough understanding of Ad interactions wi...

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Bibliographic Details
Main Authors: Erwan Sallard, Wenli Zhang, Nikita Chilakamarri, Setareh Farzanehkari, Inga Marte Charlott Seuthe, Anja Ehrhardt, Malik Aydin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
human adenovirus
saliva
oral vaccine
mucosal immunity
mucosal delivery
epithelium infection
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1579896/full
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