Dextromethorphan Suppresses Lipopolysaccharide-Induced Epigenetic Histone Regulation in the Tumor Necrosis Factor-α Expression in Primary Rat Microglia
The activation of microglial cells plays an important role in the cascade of events leading to inflammation-mediated neurodegenerative disorders. Precision therapeutics require that adjunctively feasible drugs be found to prevent microglial cell activation and prevent inflammation-mediated neuronal...
Saved in:
| Main Authors: | Yung-Ning Yang, Yu-Chen S. H. Yang, Pei-Ling Wu, Chun-Hwa Yang, Kuang-Che Kuo, San-Nan Yang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2020/9694012 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Dextromethorphan Inhibits Activations and Functions in Dendritic Cells
by: Der-Yuan Chen, et al.
Published: (2013-01-01) -
Enhanced H3K4 Trimethylation in TNF-α Promoter Gene Locus with Cell Apoptosis in the Ventral-Medial Striatum following Opioid Withdrawal of Neonatal Rat Offspring from Morphine-Addicted Mothers
by: Pei-Ling Wu, et al.
Published: (2021-01-01) -
Epigenetic regulation of histone modifications in glioblastoma: recent advances and therapeutic insights
by: Li Zhang, et al.
Published: (2025-05-01) -
Characteristics of dextromethorphan-bupropion exposures compared with exposures involving dextromethorphan alone or bupropion alone reported to United States poison centers
by: Sonia Ngo, et al.
Published: (2025-12-01) -
Mechanisms of the antiplatelet and analgesic effects of dextromethorphan and its metabolites
by: Wen-Lin Su, et al.
Published: (2020-01-01)