Control of spatiotemporal activation of organ-specific fibers in the swine vagus nerve by intermittent interferential current stimulation

Abstract Vagus nerve stimulation (VNS) is emerging as potential treatment for several chronic diseases. However, limited control of fiber activation, e.g., to promote desired effects over side effects, restricts clinical translation. Towards that goal, we describe a VNS method consisting of intermit...

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Main Authors: Nicolò Rossetti, Weiguo Song, Philipp Schnepel, Naveen Jayaprakash, Dimitrios A. Koutsouras, Mark Fichman, Jason Wong, Todd Levy, Mohamed Elgohary, Khaled Qanud, Alice Giannotti, Mary F. Barbe, Frank Liu Chen, Geert Langereis, Timir Datta-Chaudhuri, Vojkan Mihajlović, Stavros Zanos
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59595-4
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