Synthesis and structure of 6-bromo-2-(diethoxymethyl)-2-hydroxy-3-phenyl-2,3-dihydro-1H-imidazo[1,2-a]pyridin-4-ium chloride acetonitrile monosolvate

In the title solvated molecular salt, C18H22BrN2O3+·Cl−·CH3CN, the imidazole ring is in envelope conformation and the pyridine and phenyl rings are oriented at a dihedral angle of 72.52 (5)°. In the crystal, O—H...Cl and N—H...Cl hydrogen bonds link the cations and anions into centrosymmetric tetram...

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Main Authors: Firudin I. Guseinov, Aida I. Samigullina, Tuncer Hökelek, Sahil Z. Hamidov, Jamal Lasri, Khudayar I. Hasanov, Tahir A. Javadzade, Alebel N. Belay
Format: Article
Language:English
Published: International Union of Crystallography 2025-08-01
Series:Acta Crystallographica Section E: Crystallographic Communications
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Online Access:https://journals.iucr.org/paper?S2056989025005778
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Summary:In the title solvated molecular salt, C18H22BrN2O3+·Cl−·CH3CN, the imidazole ring is in envelope conformation and the pyridine and phenyl rings are oriented at a dihedral angle of 72.52 (5)°. In the crystal, O—H...Cl and N—H...Cl hydrogen bonds link the cations and anions into centrosymmetric tetramers enclosing R24(12) loops. Short Br...Cl [3.2313 (4) Å] and O...Cl [3.0490 (10) Å] contacts are observed. A Hirshfeld surface analysis of the structure indicates that the most important contributions for the crystal packing are from H...H (52.4%), H...C/C...H (12.1%), H...Br/Br...H (11.0%) and H...Cl/Cl...H (10.2%) interactions.
ISSN:2056-9890