ACTIVIN RECEPTOR LIGAND FOR THR TREATMENT OF BETA-THALASSEMIA: a SERENDIPITOUS DISCOVERY
b-thalassemia is a hereditary disorder caused by defective production of b-globin chains of hemoglobin (Hb) that leads to an increased a/b globins ratio with subsequent free a-globins. Alpha globin excess causes oxidative stress, RBCs membrane damage, premature death of late-stage erythroid precurso...
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| Main Authors: | Irene Motta, Valentina Brancaleoni, Isabella Nava, Paola Delbini, Lorena Duca |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PAGEPress Publications
2020-10-01
|
| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
| Online Access: | http://www.mjhid.org/index.php/mjhid/article/view/4358 |
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