Exploring frailty prevalence among adults in Indian healthcare settings: A systematic review and meta-analysis
Frailty is an age-associated state of increased vulnerability due to declines in physiologic systems, leading to compromised ability to withstand stressors. Given India’s rapidly aging population, our study aims to estimate the pooled prevalence of frailty and its associated factors in hospital sett...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-11-01
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| Series: | Journal of Family Medicine and Primary Care |
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| Online Access: | https://journals.lww.com/10.4103/jfmpc.jfmpc_484_24 |
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| author | Aninda Debnath Sunanda Gupta Ankit Yadav Shweta Charag Anubhav Mondal Jugal Kishore |
| author_facet | Aninda Debnath Sunanda Gupta Ankit Yadav Shweta Charag Anubhav Mondal Jugal Kishore |
| author_sort | Aninda Debnath |
| collection | DOAJ |
| description | Frailty is an age-associated state of increased vulnerability due to declines in physiologic systems, leading to compromised ability to withstand stressors. Given India’s rapidly aging population, our study aims to estimate the pooled prevalence of frailty and its associated factors in hospital settings. An extensive search was conducted across four databases, up to January 2024. A random-effects model was utilized. To quantify heterogeneity, the I² statistic, prediction interval, and the Chi-square-based Q test were employed. Outliers were identified using a Baujat plot and influence analysis. Doi plot, luis furuya kanamori (LFK) index and funnel plot were used to assess publication bias. The current meta-analysis determined a pooled frailty prevalence of 42.3% (95%CI: 34.8%−50.1%) and prefrailty prevalence of 39.8% (95%CI: 30.4%−49.8%), both exhibiting high heterogeneity (I² values of 96.9% and 95.3%, respectively). A high degree of variability was indicated by a prediction interval ranging from 9% to 76%, while Egger’s test suggested no evidence of publication bias. Our systematic review and meta-analysis, encompassing 6,856 individuals, revealed a considerable prevalence of frailty at 42.3%, underscoring its ubiquity across health spectra and demographics in India. |
| format | Article |
| id | doaj-art-1eddad3ebe824b31a8d9a8cfd3b5ae30 |
| institution | OA Journals |
| issn | 2249-4863 2278-7135 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj-art-1eddad3ebe824b31a8d9a8cfd3b5ae302025-08-20T01:59:13ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632278-71352024-11-0113114759477410.4103/jfmpc.jfmpc_484_24Exploring frailty prevalence among adults in Indian healthcare settings: A systematic review and meta-analysisAninda DebnathSunanda GuptaAnkit YadavShweta CharagAnubhav MondalJugal KishoreFrailty is an age-associated state of increased vulnerability due to declines in physiologic systems, leading to compromised ability to withstand stressors. Given India’s rapidly aging population, our study aims to estimate the pooled prevalence of frailty and its associated factors in hospital settings. An extensive search was conducted across four databases, up to January 2024. A random-effects model was utilized. To quantify heterogeneity, the I² statistic, prediction interval, and the Chi-square-based Q test were employed. Outliers were identified using a Baujat plot and influence analysis. Doi plot, luis furuya kanamori (LFK) index and funnel plot were used to assess publication bias. The current meta-analysis determined a pooled frailty prevalence of 42.3% (95%CI: 34.8%−50.1%) and prefrailty prevalence of 39.8% (95%CI: 30.4%−49.8%), both exhibiting high heterogeneity (I² values of 96.9% and 95.3%, respectively). A high degree of variability was indicated by a prediction interval ranging from 9% to 76%, while Egger’s test suggested no evidence of publication bias. Our systematic review and meta-analysis, encompassing 6,856 individuals, revealed a considerable prevalence of frailty at 42.3%, underscoring its ubiquity across health spectra and demographics in India.https://journals.lww.com/10.4103/jfmpc.jfmpc_484_24frailfrailtymeta-analysisquality of lifesystematic review |
| spellingShingle | Aninda Debnath Sunanda Gupta Ankit Yadav Shweta Charag Anubhav Mondal Jugal Kishore Exploring frailty prevalence among adults in Indian healthcare settings: A systematic review and meta-analysis Journal of Family Medicine and Primary Care frail frailty meta-analysis quality of life systematic review |
| title | Exploring frailty prevalence among adults in Indian healthcare settings: A systematic review and meta-analysis |
| title_full | Exploring frailty prevalence among adults in Indian healthcare settings: A systematic review and meta-analysis |
| title_fullStr | Exploring frailty prevalence among adults in Indian healthcare settings: A systematic review and meta-analysis |
| title_full_unstemmed | Exploring frailty prevalence among adults in Indian healthcare settings: A systematic review and meta-analysis |
| title_short | Exploring frailty prevalence among adults in Indian healthcare settings: A systematic review and meta-analysis |
| title_sort | exploring frailty prevalence among adults in indian healthcare settings a systematic review and meta analysis |
| topic | frail frailty meta-analysis quality of life systematic review |
| url | https://journals.lww.com/10.4103/jfmpc.jfmpc_484_24 |
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