Comprehensive Analysis of Thrombotic Microangiopathy Following Renal Transplantation
Conclusion: In this study, PT-TMA was associated with other risk factors besides CNI exposure, with differences by time of onset from transplantation. Prognosis was generally poor but better for early-onset PT-TMA managed with eculizumab. The development of late EPTLD in 3 patients raises concerns.
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-01-01
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| Series: | International Journal of Nephrology |
| Online Access: | http://dx.doi.org/10.1155/ijne/4396051 |
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| _version_ | 1850101404967895040 |
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| author | Ittai Fattal Tali Steinmetz Natalie Donin Ana Foigelman Tobar Benaya Rozen-Zvi Ruth Rahamimov Eviatar Nesher Idit Shirazi Eytan Mor Ilan Babai Zvi Fishelson |
| author_facet | Ittai Fattal Tali Steinmetz Natalie Donin Ana Foigelman Tobar Benaya Rozen-Zvi Ruth Rahamimov Eviatar Nesher Idit Shirazi Eytan Mor Ilan Babai Zvi Fishelson |
| author_sort | Ittai Fattal |
| collection | DOAJ |
| description | Conclusion: In this study, PT-TMA was associated with other risk factors besides CNI exposure, with differences by time of onset from transplantation. Prognosis was generally poor but better for early-onset PT-TMA managed with eculizumab. The development of late EPTLD in 3 patients raises concerns. |
| format | Article |
| id | doaj-art-1edbce4cb46b4db2b68e4d421b284cdf |
| institution | DOAJ |
| issn | 2090-2158 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Nephrology |
| spelling | doaj-art-1edbce4cb46b4db2b68e4d421b284cdf2025-08-20T02:40:02ZengWileyInternational Journal of Nephrology2090-21582024-01-01202410.1155/ijne/4396051Comprehensive Analysis of Thrombotic Microangiopathy Following Renal TransplantationIttai Fattal0Tali Steinmetz1Natalie Donin2Ana Foigelman Tobar3Benaya Rozen-Zvi4Ruth Rahamimov5Eviatar Nesher6Idit Shirazi7Eytan Mor8Ilan Babai9Zvi Fishelson10Nephrology and Hypertension UnitNephrology and Hypertension UnitDepartment of Cell and Developmental BiologyFaculty of Medical and Health SciencesNephrology and Hypertension UnitNephrology and Hypertension UnitFaculty of Medical and Health SciencesClinical Immunology LaboratoryFaculty of Medical and Health SciencesClinical Immunology LaboratoryDepartment of Cell and Developmental BiologyConclusion: In this study, PT-TMA was associated with other risk factors besides CNI exposure, with differences by time of onset from transplantation. Prognosis was generally poor but better for early-onset PT-TMA managed with eculizumab. The development of late EPTLD in 3 patients raises concerns.http://dx.doi.org/10.1155/ijne/4396051 |
| spellingShingle | Ittai Fattal Tali Steinmetz Natalie Donin Ana Foigelman Tobar Benaya Rozen-Zvi Ruth Rahamimov Eviatar Nesher Idit Shirazi Eytan Mor Ilan Babai Zvi Fishelson Comprehensive Analysis of Thrombotic Microangiopathy Following Renal Transplantation International Journal of Nephrology |
| title | Comprehensive Analysis of Thrombotic Microangiopathy Following Renal Transplantation |
| title_full | Comprehensive Analysis of Thrombotic Microangiopathy Following Renal Transplantation |
| title_fullStr | Comprehensive Analysis of Thrombotic Microangiopathy Following Renal Transplantation |
| title_full_unstemmed | Comprehensive Analysis of Thrombotic Microangiopathy Following Renal Transplantation |
| title_short | Comprehensive Analysis of Thrombotic Microangiopathy Following Renal Transplantation |
| title_sort | comprehensive analysis of thrombotic microangiopathy following renal transplantation |
| url | http://dx.doi.org/10.1155/ijne/4396051 |
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