Cariopathologic changes in human binuclear and mononuclear T-cells under the influence of cytochalasin B and lead chloride <i>in vitro</i>

The influence of PbCl2 on PHA-stimulated culture of human¢s T-cells was analyzed in the investigation. The number of mitotic cells was increased in cultures with PbCl2. Increased number of cells with morphological characteristics of apoptosis was also observed in these cultures. Addition of cytochal...

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Main Authors: M. S. Romanova, N. N. Ilyinskikh, A. G. Semenov
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2005-12-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/3696
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author M. S. Romanova
N. N. Ilyinskikh
A. G. Semenov
author_facet M. S. Romanova
N. N. Ilyinskikh
A. G. Semenov
author_sort M. S. Romanova
collection DOAJ
description The influence of PbCl2 on PHA-stimulated culture of human¢s T-cells was analyzed in the investigation. The number of mitotic cells was increased in cultures with PbCl2. Increased number of cells with morphological characteristics of apoptosis was also observed in these cultures. Addition of cytochalasin B lead to intensification of cell¢s death under the influence of lead chloride.
format Article
id doaj-art-1ed93ace7df34b8399a28c90f0bd40b1
institution Kabale University
issn 1682-0363
1819-3684
language English
publishDate 2005-12-01
publisher Siberian State Medical University (Tomsk)
record_format Article
series Бюллетень сибирской медицины
spelling doaj-art-1ed93ace7df34b8399a28c90f0bd40b12025-08-20T04:00:18ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842005-12-0144596410.20538/1682-0363-2005-4-59-642335Cariopathologic changes in human binuclear and mononuclear T-cells under the influence of cytochalasin B and lead chloride <i>in vitro</i>M. S. Romanova0N. N. Ilyinskikh1A. G. Semenov2Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетThe influence of PbCl2 on PHA-stimulated culture of human¢s T-cells was analyzed in the investigation. The number of mitotic cells was increased in cultures with PbCl2. Increased number of cells with morphological characteristics of apoptosis was also observed in these cultures. Addition of cytochalasin B lead to intensification of cell¢s death under the influence of lead chloride.https://bulletin.ssmu.ru/jour/article/view/3696culture of t-cellslead chloridecytochalasin bpathology of nucleimitotic activity
spellingShingle M. S. Romanova
N. N. Ilyinskikh
A. G. Semenov
Cariopathologic changes in human binuclear and mononuclear T-cells under the influence of cytochalasin B and lead chloride <i>in vitro</i>
Бюллетень сибирской медицины
culture of t-cells
lead chloride
cytochalasin b
pathology of nuclei
mitotic activity
title Cariopathologic changes in human binuclear and mononuclear T-cells under the influence of cytochalasin B and lead chloride <i>in vitro</i>
title_full Cariopathologic changes in human binuclear and mononuclear T-cells under the influence of cytochalasin B and lead chloride <i>in vitro</i>
title_fullStr Cariopathologic changes in human binuclear and mononuclear T-cells under the influence of cytochalasin B and lead chloride <i>in vitro</i>
title_full_unstemmed Cariopathologic changes in human binuclear and mononuclear T-cells under the influence of cytochalasin B and lead chloride <i>in vitro</i>
title_short Cariopathologic changes in human binuclear and mononuclear T-cells under the influence of cytochalasin B and lead chloride <i>in vitro</i>
title_sort cariopathologic changes in human binuclear and mononuclear t cells under the influence of cytochalasin b and lead chloride i in vitro i
topic culture of t-cells
lead chloride
cytochalasin b
pathology of nuclei
mitotic activity
url https://bulletin.ssmu.ru/jour/article/view/3696
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AT nnilyinskikh cariopathologicchangesinhumanbinuclearandmononucleartcellsundertheinfluenceofcytochalasinbandleadchlorideiinvitroi
AT agsemenov cariopathologicchangesinhumanbinuclearandmononucleartcellsundertheinfluenceofcytochalasinbandleadchlorideiinvitroi