Development and application of an efficient, accurate, and environmentally friendly liquid chromatography–tandem mass spectrometry method for the determination of five Alternaria toxins in wheat
The contamination of Alternaria toxins poses a potential risk to human health. This study developed a rapid, efficient, and environmentally friendly method for the simultaneous determination of five types of Alternaria toxins in wheat using high-precision and stable isotope liquid chromatography tan...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-01-01
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| Series: | Food Chemistry: X |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590157525000136 |
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| author | Huiyuan Lang Zengwang Guo Yu Wu Li Li Hongmei Liu Lianzhou Jiang Songxue Wang Jin Ye |
| author_facet | Huiyuan Lang Zengwang Guo Yu Wu Li Li Hongmei Liu Lianzhou Jiang Songxue Wang Jin Ye |
| author_sort | Huiyuan Lang |
| collection | DOAJ |
| description | The contamination of Alternaria toxins poses a potential risk to human health. This study developed a rapid, efficient, and environmentally friendly method for the simultaneous determination of five types of Alternaria toxins in wheat using high-precision and stable isotope liquid chromatography tandem mass spectrometry. The comparison between dilution method and solid-phase extraction method shows that the former achieves satisfactory results with a simple and convenient sample purification method. The quantitative limit range is 0.88 to 1.68 μg/kg. The recoveries are between 81.40% and 102.68%, with RSD less than 11.95%. The method was used to analyze 60 samples from the main wheat producing areas in China. The results showed that Tenuzonic acid had the highest detection rate (100%), followed by Tentoxin (95%), Alternariol (66.67%), and Alternariol monomethyl ether (53.33%). There is a certain pollution risk that needs to be taken seriously and monitoring should be strengthened. |
| format | Article |
| id | doaj-art-1ed8fe4b4891424aa4e85425f32c483f |
| institution | Kabale University |
| issn | 2590-1575 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry: X |
| spelling | doaj-art-1ed8fe4b4891424aa4e85425f32c483f2025-02-12T05:32:19ZengElsevierFood Chemistry: X2590-15752025-01-0125102167Development and application of an efficient, accurate, and environmentally friendly liquid chromatography–tandem mass spectrometry method for the determination of five Alternaria toxins in wheatHuiyuan Lang0Zengwang Guo1Yu Wu2Li Li3Hongmei Liu4Lianzhou Jiang5Songxue Wang6Jin Ye7College of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, ChinaCollege of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China; Heilongjiang Grain and Oil Food Safety Testing Industry Technology Research Institute, Harbin, Heilongjiang 150030, ChinaAcademy of National Food and Strategic Reserves Administration, NFSRA Key Laboratory of Grain and oil quality and safety, Beijing 100037, ChinaAcademy of National Food and Strategic Reserves Administration, NFSRA Key Laboratory of Grain and oil quality and safety, Beijing 100037, China; Corresponding authors.Academy of National Food and Strategic Reserves Administration, NFSRA Key Laboratory of Grain and oil quality and safety, Beijing 100037, ChinaCollege of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, China; Corresponding authors.Academy of National Food and Strategic Reserves Administration, NFSRA Key Laboratory of Grain and oil quality and safety, Beijing 100037, ChinaAcademy of National Food and Strategic Reserves Administration, NFSRA Key Laboratory of Grain and oil quality and safety, Beijing 100037, China; Corresponding authors.The contamination of Alternaria toxins poses a potential risk to human health. This study developed a rapid, efficient, and environmentally friendly method for the simultaneous determination of five types of Alternaria toxins in wheat using high-precision and stable isotope liquid chromatography tandem mass spectrometry. The comparison between dilution method and solid-phase extraction method shows that the former achieves satisfactory results with a simple and convenient sample purification method. The quantitative limit range is 0.88 to 1.68 μg/kg. The recoveries are between 81.40% and 102.68%, with RSD less than 11.95%. The method was used to analyze 60 samples from the main wheat producing areas in China. The results showed that Tenuzonic acid had the highest detection rate (100%), followed by Tentoxin (95%), Alternariol (66.67%), and Alternariol monomethyl ether (53.33%). There is a certain pollution risk that needs to be taken seriously and monitoring should be strengthened.http://www.sciencedirect.com/science/article/pii/S2590157525000136WheatAlternaria toxinsDilution methodLC-MS/MSContamination assessment |
| spellingShingle | Huiyuan Lang Zengwang Guo Yu Wu Li Li Hongmei Liu Lianzhou Jiang Songxue Wang Jin Ye Development and application of an efficient, accurate, and environmentally friendly liquid chromatography–tandem mass spectrometry method for the determination of five Alternaria toxins in wheat Food Chemistry: X Wheat Alternaria toxins Dilution method LC-MS/MS Contamination assessment |
| title | Development and application of an efficient, accurate, and environmentally friendly liquid chromatography–tandem mass spectrometry method for the determination of five Alternaria toxins in wheat |
| title_full | Development and application of an efficient, accurate, and environmentally friendly liquid chromatography–tandem mass spectrometry method for the determination of five Alternaria toxins in wheat |
| title_fullStr | Development and application of an efficient, accurate, and environmentally friendly liquid chromatography–tandem mass spectrometry method for the determination of five Alternaria toxins in wheat |
| title_full_unstemmed | Development and application of an efficient, accurate, and environmentally friendly liquid chromatography–tandem mass spectrometry method for the determination of five Alternaria toxins in wheat |
| title_short | Development and application of an efficient, accurate, and environmentally friendly liquid chromatography–tandem mass spectrometry method for the determination of five Alternaria toxins in wheat |
| title_sort | development and application of an efficient accurate and environmentally friendly liquid chromatography tandem mass spectrometry method for the determination of five alternaria toxins in wheat |
| topic | Wheat Alternaria toxins Dilution method LC-MS/MS Contamination assessment |
| url | http://www.sciencedirect.com/science/article/pii/S2590157525000136 |
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