Ultrasound-assisted green syntheses of novel pyrimidine derivatives and their comparison with conventional methods
Ultrasound-assisted green syntheses of novel potentially bioactive pyrimidine derivatives have been carried out. The same compounds were obtained by conventional methods of synthesis, and the reaction times and yields of final products obtained by these two methods were compared. It was found that t...
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| Format: | Article |
| Language: | English |
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Springer
2023-05-01
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| Series: | Journal of Saudi Chemical Society |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1319610323000327 |
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| author | Vergush A. Pivazyan Emma A. Ghazaryan Armen V. Karapetyan Roza S. Shainova Siranush V. Harutyunyan Asya S. Vorskanyan Aleksandr P. Yengoyan Tiruhi A. Gomktsyan |
| author_facet | Vergush A. Pivazyan Emma A. Ghazaryan Armen V. Karapetyan Roza S. Shainova Siranush V. Harutyunyan Asya S. Vorskanyan Aleksandr P. Yengoyan Tiruhi A. Gomktsyan |
| author_sort | Vergush A. Pivazyan |
| collection | DOAJ |
| description | Ultrasound-assisted green syntheses of novel potentially bioactive pyrimidine derivatives have been carried out. The same compounds were obtained by conventional methods of synthesis, and the reaction times and yields of final products obtained by these two methods were compared. It was found that the time of utrasound-promoted reactions was reduced by almost 6–96 times, and their yields were equal or turn out to be greater compared to the traditional approach. The synthesized compounds showed a pronounced stimulating effect on plant growth. The most active derivatives were selected for deeper biological studies and subsequent field trials. |
| format | Article |
| id | doaj-art-1ed104bd41b24049879266bd07d3dbcf |
| institution | Kabale University |
| issn | 1319-6103 |
| language | English |
| publishDate | 2023-05-01 |
| publisher | Springer |
| record_format | Article |
| series | Journal of Saudi Chemical Society |
| spelling | doaj-art-1ed104bd41b24049879266bd07d3dbcf2025-08-20T03:54:57ZengSpringerJournal of Saudi Chemical Society1319-61032023-05-0127310162810.1016/j.jscs.2023.101628Ultrasound-assisted green syntheses of novel pyrimidine derivatives and their comparison with conventional methodsVergush A. Pivazyan0Emma A. Ghazaryan1Armen V. Karapetyan2Roza S. Shainova3Siranush V. Harutyunyan4Asya S. Vorskanyan5Aleksandr P. Yengoyan6Tiruhi A. Gomktsyan7Department for Pesticides Synthesis and Expertise, National Agrarian University of Armenia, Teryan 74, Yerevan 0009, ArmeniaDepartment for Pesticides Synthesis and Expertise, National Agrarian University of Armenia, Teryan 74, Yerevan 0009, ArmeniaDepartment for Pesticides Synthesis and Expertise, National Agrarian University of Armenia, Teryan 74, Yerevan 0009, ArmeniaDepartment for Pesticides Synthesis and Expertise, National Agrarian University of Armenia, Teryan 74, Yerevan 0009, ArmeniaDepartment for Pesticides Synthesis and Expertise, National Agrarian University of Armenia, Teryan 74, Yerevan 0009, ArmeniaDepartment for Pesticides Synthesis and Expertise, National Agrarian University of Armenia, Teryan 74, Yerevan 0009, ArmeniaCorresponding author.; Department for Pesticides Synthesis and Expertise, National Agrarian University of Armenia, Teryan 74, Yerevan 0009, ArmeniaDepartment for Pesticides Synthesis and Expertise, National Agrarian University of Armenia, Teryan 74, Yerevan 0009, ArmeniaUltrasound-assisted green syntheses of novel potentially bioactive pyrimidine derivatives have been carried out. The same compounds were obtained by conventional methods of synthesis, and the reaction times and yields of final products obtained by these two methods were compared. It was found that the time of utrasound-promoted reactions was reduced by almost 6–96 times, and their yields were equal or turn out to be greater compared to the traditional approach. The synthesized compounds showed a pronounced stimulating effect on plant growth. The most active derivatives were selected for deeper biological studies and subsequent field trials.http://www.sciencedirect.com/science/article/pii/S1319610323000327Plant growth stimulant activityPyrimidine derivativesSonochemical synthesisTraditional synthesis |
| spellingShingle | Vergush A. Pivazyan Emma A. Ghazaryan Armen V. Karapetyan Roza S. Shainova Siranush V. Harutyunyan Asya S. Vorskanyan Aleksandr P. Yengoyan Tiruhi A. Gomktsyan Ultrasound-assisted green syntheses of novel pyrimidine derivatives and their comparison with conventional methods Journal of Saudi Chemical Society Plant growth stimulant activity Pyrimidine derivatives Sonochemical synthesis Traditional synthesis |
| title | Ultrasound-assisted green syntheses of novel pyrimidine derivatives and their comparison with conventional methods |
| title_full | Ultrasound-assisted green syntheses of novel pyrimidine derivatives and their comparison with conventional methods |
| title_fullStr | Ultrasound-assisted green syntheses of novel pyrimidine derivatives and their comparison with conventional methods |
| title_full_unstemmed | Ultrasound-assisted green syntheses of novel pyrimidine derivatives and their comparison with conventional methods |
| title_short | Ultrasound-assisted green syntheses of novel pyrimidine derivatives and their comparison with conventional methods |
| title_sort | ultrasound assisted green syntheses of novel pyrimidine derivatives and their comparison with conventional methods |
| topic | Plant growth stimulant activity Pyrimidine derivatives Sonochemical synthesis Traditional synthesis |
| url | http://www.sciencedirect.com/science/article/pii/S1319610323000327 |
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