A comparison of the alterations of oral microbiome with fixed orthodontic therapy and clear aligners: a systematic review
Aim The oral microbiome plays a fundamental role in maintaining homeostasis of the oral cavity. In the last decade there has been an increasing use of clear aligners, which guarantee aesthetics and comfort for the patient. The aim of this work is to conduct a systematic review regarding the alterati...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Journal of Oral Microbiology |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/20002297.2024.2372751 |
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| author | Alessandra Lucchese Marta Marcolina Nicasio Mancini Roberto Ferrarese Serena Acconciaioco Enrico Gherlone Chiara Bonini Maurizio Manuelli Antonella Polimeni |
| author_facet | Alessandra Lucchese Marta Marcolina Nicasio Mancini Roberto Ferrarese Serena Acconciaioco Enrico Gherlone Chiara Bonini Maurizio Manuelli Antonella Polimeni |
| author_sort | Alessandra Lucchese |
| collection | DOAJ |
| description | Aim The oral microbiome plays a fundamental role in maintaining homeostasis of the oral cavity. In the last decade there has been an increasing use of clear aligners, which guarantee aesthetics and comfort for the patient. The aim of this work is to conduct a systematic review regarding the alterations in bacterial flora and oral health with aligner and fixed orthodontic therapy.Design A systematic review was conducted following the PRISMA Statement. Using the search strategy “(clear aligners OR Invisalign) AND (fixed therapy OR fixed orthodont * therapy) NOT (thermoplastic retainers) AND (oral microbiome OR oral microbiota * OR oral microbiology * OR oral health)”, in the main scientific databases. Two scales were applied to assess the quality of scientific evidence: ROBINS-I and RoB 2.Results A total of 484 articles emerged of which 9 met our inclusion/exclusion criteria. Afterwards the application of the rating scales, 1 article was found to be at low risk of bias, 6 at moderate and 2 at serious risk of bias.Conclusion Both therapies cause an alteration of the oral microbiome, but the changes induced by the aligners seem to be compatible with a better oral health compared to fixed appliances. |
| format | Article |
| id | doaj-art-1ec8832375174d7cb3fa4f53c91f1055 |
| institution | Kabale University |
| issn | 2000-2297 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Oral Microbiology |
| spelling | doaj-art-1ec8832375174d7cb3fa4f53c91f10552025-02-02T00:00:47ZengTaylor & Francis GroupJournal of Oral Microbiology2000-22972025-12-0117110.1080/20002297.2024.2372751A comparison of the alterations of oral microbiome with fixed orthodontic therapy and clear aligners: a systematic reviewAlessandra Lucchese0Marta Marcolina1Nicasio Mancini2Roberto Ferrarese3Serena Acconciaioco4Enrico Gherlone5Chiara Bonini6Maurizio Manuelli7Antonella Polimeni8Department of Life Sciences, Health and Healthcare Professions, Link Campus University, Rome, ItalyDepartment of Life Sciences, Health and Healthcare Professions, Link Campus University, Rome, ItalyDepartment of Medicine and Innovation Technology, University of Insubria (DIMIT), Varese, ItalyIRCCS Ospedale San Raffaele, Milan, ItalyDepartment of Life Sciences, Health and Healthcare Professions, Link Campus University, Rome, ItalyUnit of Orthodontics, Division of Dentistry, IRCSS Ospedale San Raffaele Scientific Institute, Milan, ItalyExperimental Hematology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan, ItalyDepartment of Life Sciences, Health and Healthcare Professions, Link Campus University, Rome, ItalyDepartment of Oral and Maxillo-Facial Sciences, Sapienza University of Rome, Rome, ItalyAim The oral microbiome plays a fundamental role in maintaining homeostasis of the oral cavity. In the last decade there has been an increasing use of clear aligners, which guarantee aesthetics and comfort for the patient. The aim of this work is to conduct a systematic review regarding the alterations in bacterial flora and oral health with aligner and fixed orthodontic therapy.Design A systematic review was conducted following the PRISMA Statement. Using the search strategy “(clear aligners OR Invisalign) AND (fixed therapy OR fixed orthodont * therapy) NOT (thermoplastic retainers) AND (oral microbiome OR oral microbiota * OR oral microbiology * OR oral health)”, in the main scientific databases. Two scales were applied to assess the quality of scientific evidence: ROBINS-I and RoB 2.Results A total of 484 articles emerged of which 9 met our inclusion/exclusion criteria. Afterwards the application of the rating scales, 1 article was found to be at low risk of bias, 6 at moderate and 2 at serious risk of bias.Conclusion Both therapies cause an alteration of the oral microbiome, but the changes induced by the aligners seem to be compatible with a better oral health compared to fixed appliances.https://www.tandfonline.com/doi/10.1080/20002297.2024.2372751Oral microbiomeclear alignersorthodontic appliancesoral healthsystematic review |
| spellingShingle | Alessandra Lucchese Marta Marcolina Nicasio Mancini Roberto Ferrarese Serena Acconciaioco Enrico Gherlone Chiara Bonini Maurizio Manuelli Antonella Polimeni A comparison of the alterations of oral microbiome with fixed orthodontic therapy and clear aligners: a systematic review Journal of Oral Microbiology Oral microbiome clear aligners orthodontic appliances oral health systematic review |
| title | A comparison of the alterations of oral microbiome with fixed orthodontic therapy and clear aligners: a systematic review |
| title_full | A comparison of the alterations of oral microbiome with fixed orthodontic therapy and clear aligners: a systematic review |
| title_fullStr | A comparison of the alterations of oral microbiome with fixed orthodontic therapy and clear aligners: a systematic review |
| title_full_unstemmed | A comparison of the alterations of oral microbiome with fixed orthodontic therapy and clear aligners: a systematic review |
| title_short | A comparison of the alterations of oral microbiome with fixed orthodontic therapy and clear aligners: a systematic review |
| title_sort | comparison of the alterations of oral microbiome with fixed orthodontic therapy and clear aligners a systematic review |
| topic | Oral microbiome clear aligners orthodontic appliances oral health systematic review |
| url | https://www.tandfonline.com/doi/10.1080/20002297.2024.2372751 |
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