Isolation and identification of a red pigment producer endophytic fungus Monascus sanguineus from Rehmannia glutinosa Libosch

Fungal pigments are the potential resources as a natural food colorant. An endophytic fungus RJL03, which is able to produce abundant soluble red pigments, was isolated from the medicinal plant Rehmannia glutinosa Libosch. For further research and utilization of this strain and its secondary metabol...

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Main Authors: HE Yatao, GAO Dandan, GAN Senning, SUN Ting, CAI Kuizheng, LIU Junlin
Format: Article
Language:English
Published: Zhejiang University Press 2019-02-01
Series:浙江大学学报. 农业与生命科学版
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Online Access:https://www.academax.com/doi/10.3785/j.issn.1008-9209.2018.02.022
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author HE Yatao
GAO Dandan
GAN Senning
SUN Ting
CAI Kuizheng
LIU Junlin
author_facet HE Yatao
GAO Dandan
GAN Senning
SUN Ting
CAI Kuizheng
LIU Junlin
author_sort HE Yatao
collection DOAJ
description Fungal pigments are the potential resources as a natural food colorant. An endophytic fungus RJL03, which is able to produce abundant soluble red pigments, was isolated from the medicinal plant Rehmannia glutinosa Libosch. For further research and utilization of this strain and its secondary metabolites, morphological and molecular characteristics of RJL03 were identified. For observing the colonial morphology, the strain was cultured on different substrates at 25℃ for seven days. The fungus was also observed through light microscope and scanning electron microscope. The colony of this fungus was white at first and turned red at later stage, villous, circular; the mycelium was composed of irregularly branched, septate; conidia had borne terminally on pedicels, single or 2-10 in chain, which was about (8.0-16.5) μm×(7.5-14.0) μm; the cleistothecia was globose, brown, arising terminally from the apex of short hyphae, whose diameter was 32-70 μm; the ascospore was ellipsoidal, smooth, colorless or red, which was about (6.0-7.5) μm×(4.0-5.0) μm. Sequence analysis showed that ITS and 18S of the strain had 100% and 93% similarities with Monascus sanguineus, respectively. In conclusion, morphological results and phylogenetic analysis provided great evidence that endophytic fungus RJL03 was M. sanguineus. This study first reported M. sanguineus isolates from Rehmannia glutinosa Libosch. in China. It is considered that M. sanguineus, unlike M. purpureus, should be an independent species.
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spelling doaj-art-1eb861c192f94ec9928d8c11f55da3bb2025-08-20T03:16:03ZengZhejiang University Press浙江大学学报. 农业与生命科学版1008-92092097-51552019-02-01451710.3785/j.issn.1008-9209.2018.02.02210089209Isolation and identification of a red pigment producer endophytic fungus Monascus sanguineus from Rehmannia glutinosa LiboschHE YataoGAO DandanGAN SenningSUN TingCAI KuizhengLIU JunlinFungal pigments are the potential resources as a natural food colorant. An endophytic fungus RJL03, which is able to produce abundant soluble red pigments, was isolated from the medicinal plant Rehmannia glutinosa Libosch. For further research and utilization of this strain and its secondary metabolites, morphological and molecular characteristics of RJL03 were identified. For observing the colonial morphology, the strain was cultured on different substrates at 25℃ for seven days. The fungus was also observed through light microscope and scanning electron microscope. The colony of this fungus was white at first and turned red at later stage, villous, circular; the mycelium was composed of irregularly branched, septate; conidia had borne terminally on pedicels, single or 2-10 in chain, which was about (8.0-16.5) μm×(7.5-14.0) μm; the cleistothecia was globose, brown, arising terminally from the apex of short hyphae, whose diameter was 32-70 μm; the ascospore was ellipsoidal, smooth, colorless or red, which was about (6.0-7.5) μm×(4.0-5.0) μm. Sequence analysis showed that ITS and 18S of the strain had 100% and 93% similarities with Monascus sanguineus, respectively. In conclusion, morphological results and phylogenetic analysis provided great evidence that endophytic fungus RJL03 was M. sanguineus. This study first reported M. sanguineus isolates from Rehmannia glutinosa Libosch. in China. It is considered that M. sanguineus, unlike M. purpureus, should be an independent species.https://www.academax.com/doi/10.3785/j.issn.1008-9209.2018.02.022endophytic fungired pigment<italic>Rehmannia glutinosa</italic> Libosch.<italic>Monascus</italic>isolation and identification
spellingShingle HE Yatao
GAO Dandan
GAN Senning
SUN Ting
CAI Kuizheng
LIU Junlin
Isolation and identification of a red pigment producer endophytic fungus Monascus sanguineus from Rehmannia glutinosa Libosch
浙江大学学报. 农业与生命科学版
endophytic fungi
red pigment
<italic>Rehmannia glutinosa</italic> Libosch.
<italic>Monascus</italic>
isolation and identification
title Isolation and identification of a red pigment producer endophytic fungus Monascus sanguineus from Rehmannia glutinosa Libosch
title_full Isolation and identification of a red pigment producer endophytic fungus Monascus sanguineus from Rehmannia glutinosa Libosch
title_fullStr Isolation and identification of a red pigment producer endophytic fungus Monascus sanguineus from Rehmannia glutinosa Libosch
title_full_unstemmed Isolation and identification of a red pigment producer endophytic fungus Monascus sanguineus from Rehmannia glutinosa Libosch
title_short Isolation and identification of a red pigment producer endophytic fungus Monascus sanguineus from Rehmannia glutinosa Libosch
title_sort isolation and identification of a red pigment producer endophytic fungus monascus sanguineus from rehmannia glutinosa libosch
topic endophytic fungi
red pigment
<italic>Rehmannia glutinosa</italic> Libosch.
<italic>Monascus</italic>
isolation and identification
url https://www.academax.com/doi/10.3785/j.issn.1008-9209.2018.02.022
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