Mechanistic insights into Nrf2-driven pathogenesis and therapeutic targeting in spinal cord injury

Mechanistic insights into Nrf2-driven pathogenesis and therapeutic targeting in spinal cord injury

Spinal cord injury (SCI) is a traumatic disease of the central nervous system that can result in significant tissue damage and neurological dysfunction. The pathophysiological process of SCI encompasses both primary and secondary injuries, involving various pathological mechanisms such as oxidative...

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Bibliographic Details
Main Authors: Tao Xie, Jiyu Xu, Xinyu Liu, Yaquan Yu, Yang Lu, Tao Wang, Feng Gao, Hui Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
spinal cord injury
Nrf2
oxidative stress
inflammation
ferroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574834/full
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