Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: Emerging Nootropics of Abuse

This case report describes the development of withdrawal from phenibut, a gamma-aminobutyric acid-receptor type B agonist. Although phenibut is not an FDA-approved medication, it is available through online retailers as a nootropic supplement. There are reports of dependence in patients that misuse...

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Main Authors: Tania Ahuja, Ofole Mgbako, Caroline Katzman, Allison Grossman
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2018/9864285
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author Tania Ahuja
Ofole Mgbako
Caroline Katzman
Allison Grossman
author_facet Tania Ahuja
Ofole Mgbako
Caroline Katzman
Allison Grossman
author_sort Tania Ahuja
collection DOAJ
description This case report describes the development of withdrawal from phenibut, a gamma-aminobutyric acid-receptor type B agonist. Although phenibut is not an FDA-approved medication, it is available through online retailers as a nootropic supplement. There are reports of dependence in patients that misuse phenibut. We report a case in which a patient experienced withdrawal symptoms from phenibut and was successfully treated with a baclofen taper. This case report highlights the development of phenibut use disorder with coingestion of alcohol and potential management for phenibut withdrawal. We believe clinicians must be aware of how phenibut dependence may present and how to manage the withdrawal syndrome.
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institution Kabale University
issn 2090-682X
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language English
publishDate 2018-01-01
publisher Wiley
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series Case Reports in Psychiatry
spelling doaj-art-1e9a230210df45e99a6dae6fd7f5d23f2025-02-03T00:59:04ZengWileyCase Reports in Psychiatry2090-682X2090-68382018-01-01201810.1155/2018/98642859864285Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: Emerging Nootropics of AbuseTania Ahuja0Ofole Mgbako1Caroline Katzman2Allison Grossman3Department of Pharmacy, New York University Langone Health, 550 First Avenue, New York, NY 10016, USADepartment of Medicine, New York University Langone Health, 550 First Avenue, New York, NY 10016, USANew York University School of Medicine, 550 First Avenue, New York, NY 10016, USADepartment of Psychiatry, New York University Langone Health, 550 First Avenue, New York, NY 10016, USAThis case report describes the development of withdrawal from phenibut, a gamma-aminobutyric acid-receptor type B agonist. Although phenibut is not an FDA-approved medication, it is available through online retailers as a nootropic supplement. There are reports of dependence in patients that misuse phenibut. We report a case in which a patient experienced withdrawal symptoms from phenibut and was successfully treated with a baclofen taper. This case report highlights the development of phenibut use disorder with coingestion of alcohol and potential management for phenibut withdrawal. We believe clinicians must be aware of how phenibut dependence may present and how to manage the withdrawal syndrome.http://dx.doi.org/10.1155/2018/9864285
spellingShingle Tania Ahuja
Ofole Mgbako
Caroline Katzman
Allison Grossman
Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: Emerging Nootropics of Abuse
Case Reports in Psychiatry
title Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: Emerging Nootropics of Abuse
title_full Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: Emerging Nootropics of Abuse
title_fullStr Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: Emerging Nootropics of Abuse
title_full_unstemmed Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: Emerging Nootropics of Abuse
title_short Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: Emerging Nootropics of Abuse
title_sort phenibut β phenyl γ aminobutyric acid dependence and management of withdrawal emerging nootropics of abuse
url http://dx.doi.org/10.1155/2018/9864285
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