Non-linear relationship between social jetlag and depressive symptoms among Chinese college students

Abstract This study aims to elucidate the relationship between social jetlag and depressive symptoms in college students, with a focus on identifying specific cut points that significantly heighten the risk of depression. A cross-sectional study was conducted among 2,006 students from Jiangsu Colleg...

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Main Authors: Jing Luo, Jinyou Yang, Tianjiao Dai, Jing Zhao, Shasha Wu, Linlu Zhou, Hong Ge, Beilei Yan, Yunyun Liu, Yuling Zhang, Jiru Wang, Wenqin Yin, Qiuxia Ren, Song Lin
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Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-03371-3
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author Jing Luo
Jinyou Yang
Tianjiao Dai
Jing Zhao
Shasha Wu
Linlu Zhou
Hong Ge
Beilei Yan
Yunyun Liu
Yuling Zhang
Jiru Wang
Wenqin Yin
Qiuxia Ren
Song Lin
author_facet Jing Luo
Jinyou Yang
Tianjiao Dai
Jing Zhao
Shasha Wu
Linlu Zhou
Hong Ge
Beilei Yan
Yunyun Liu
Yuling Zhang
Jiru Wang
Wenqin Yin
Qiuxia Ren
Song Lin
author_sort Jing Luo
collection DOAJ
description Abstract This study aims to elucidate the relationship between social jetlag and depressive symptoms in college students, with a focus on identifying specific cut points that significantly heighten the risk of depression. A cross-sectional study was conducted among 2,006 students from Jiangsu College of Nursing between October and November 2024. Social jetlag was calculated based on the difference between the midpoints of sleep on workdays and weekends. Depressive symptoms were assessed using the Patient Health Questionnaire-9 (PHQ-9). Multivariate logistic regression was applied to examine the relationship between social jetlag and depressive symptoms, adjusting for potential confounders. The prevalence of depressive symptoms (PHQ-9 ≥ 10) among participants was 10.1%. A non-linear relationship was observed between social jetlag and depressive symptoms, with the risk of depression increasing significantly beyond a threshold of 1.2 h of social jetlag. Specifically, individuals with social jetlag ≥ 1.2 h had 72% higher odds of depressive symptoms compared to those with lower levels (OR = 1.72, 95% CI: 1.24–2.38). Subgroup analyses revealed that this association was consistent across both grade and gender. Sensitivity analyses further affirmed the robustness of these findings. This study suggests a non-linear association between social jetlag and depressive symptoms in college students, with a marked increase in depression risk for those with social jetlag ≥ 1.2 h. Longitudinal studies are needed to clarify the causal pathways and identify modifiable factors for targeted interventions.
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spelling doaj-art-1e9381ac214f4e36a049ebeeb9ead0c92025-08-20T03:16:31ZengNature PortfolioScientific Reports2045-23222025-05-011511810.1038/s41598-025-03371-3Non-linear relationship between social jetlag and depressive symptoms among Chinese college studentsJing Luo0Jinyou Yang1Tianjiao Dai2Jing Zhao3Shasha Wu4Linlu Zhou5Hong Ge6Beilei Yan7Yunyun Liu8Yuling Zhang9Jiru Wang10Wenqin Yin11Qiuxia Ren12Song Lin13Jiangsu College of NursingJiangsu College of NursingJiangsu College of NursingJiangsu College of NursingJiangsu College of NursingJiangsu College of NursingJiangsu College of NursingJiangsu College of NursingJiangsu College of NursingJiangsu College of NursingJiangsu College of NursingJiangsu College of NursingJiangsu College of NursingThe Affiliated Huai’an No. 1 People’s Hospital of Nanjing Medical UniversityAbstract This study aims to elucidate the relationship between social jetlag and depressive symptoms in college students, with a focus on identifying specific cut points that significantly heighten the risk of depression. A cross-sectional study was conducted among 2,006 students from Jiangsu College of Nursing between October and November 2024. Social jetlag was calculated based on the difference between the midpoints of sleep on workdays and weekends. Depressive symptoms were assessed using the Patient Health Questionnaire-9 (PHQ-9). Multivariate logistic regression was applied to examine the relationship between social jetlag and depressive symptoms, adjusting for potential confounders. The prevalence of depressive symptoms (PHQ-9 ≥ 10) among participants was 10.1%. A non-linear relationship was observed between social jetlag and depressive symptoms, with the risk of depression increasing significantly beyond a threshold of 1.2 h of social jetlag. Specifically, individuals with social jetlag ≥ 1.2 h had 72% higher odds of depressive symptoms compared to those with lower levels (OR = 1.72, 95% CI: 1.24–2.38). Subgroup analyses revealed that this association was consistent across both grade and gender. Sensitivity analyses further affirmed the robustness of these findings. This study suggests a non-linear association between social jetlag and depressive symptoms in college students, with a marked increase in depression risk for those with social jetlag ≥ 1.2 h. Longitudinal studies are needed to clarify the causal pathways and identify modifiable factors for targeted interventions.https://doi.org/10.1038/s41598-025-03371-3DepressionSleepSocial jetlagStudentNon-linearCross-sectional
spellingShingle Jing Luo
Jinyou Yang
Tianjiao Dai
Jing Zhao
Shasha Wu
Linlu Zhou
Hong Ge
Beilei Yan
Yunyun Liu
Yuling Zhang
Jiru Wang
Wenqin Yin
Qiuxia Ren
Song Lin
Non-linear relationship between social jetlag and depressive symptoms among Chinese college students
Scientific Reports
Depression
Sleep
Social jetlag
Student
Non-linear
Cross-sectional
title Non-linear relationship between social jetlag and depressive symptoms among Chinese college students
title_full Non-linear relationship between social jetlag and depressive symptoms among Chinese college students
title_fullStr Non-linear relationship between social jetlag and depressive symptoms among Chinese college students
title_full_unstemmed Non-linear relationship between social jetlag and depressive symptoms among Chinese college students
title_short Non-linear relationship between social jetlag and depressive symptoms among Chinese college students
title_sort non linear relationship between social jetlag and depressive symptoms among chinese college students
topic Depression
Sleep
Social jetlag
Student
Non-linear
Cross-sectional
url https://doi.org/10.1038/s41598-025-03371-3
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