Clinicopathological features of 60 cases of asymptomatic hematuria and/or proteinuria
Objective To investigate the clinicopathological features of asymptomatic hematuria and/or proteinuria.Methods The clinicopathological features were analyzed and correlated in 60 cases of asymptomatic hematuria and/or proteinuria.According to 24-h urine protein excretion >150 mg,60 cases were div...
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| Main Authors: | , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Clinical Nephrology
2016-01-01
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| Series: | Linchuang shenzangbing zazhi |
| Subjects: | |
| Online Access: | http://www.lcszb.com/thesisDetails?columnId=57919376&Fpath=home&index=0 |
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| Summary: | Objective To investigate the clinicopathological features of asymptomatic hematuria and/or proteinuria.Methods The clinicopathological features were analyzed and correlated in 60 cases of asymptomatic hematuria and/or proteinuria.According to 24-h urine protein excretion >150 mg,60 cases were divided into simple hematuria group(n= 14,6 males and 8 females) and proteinuria groupCsimple proteinuria or proteinuria with hematuria)(n = 46,18 males and 28 females).The study population also was divided into IgA nephropathy group(n = 36,11 males and 25 females) and nonIgA nephropathy group(n=24,13 males and 11 females) by mesangial IgA deposition,and the statistical analysis was carried out respectively.Results The pathological features in proteinuria group were more severe and serum uric acid was higher in proteinuria group than in simple hematuria group[(305.5 ± 90.8) vs.(376.7 + 86.7) μmol/L,t=-2.27,P = 0.03],showed statistical significant difference,but there were no differences in serum creatinine,Cystatin C(CysC),serum IgA and complement C3.The creatinine levels of IgA nephropathy group was higher than Non-IgA nephropathy[(71.5 + 21.6) vs.(59.2 ± 14.8) μmol/L,t = 2.09,P = 0.04],but no differences in Cys C,serum uric acid,serum IgA Complement C3 and 24-hour urinary protein.Moreover,except 24-hour urinary protein,all the values were within the normal range of reference values.Conclusions Renal lesion can not be sensitively marked by clinical features,such as serum creatinine,Cys C,serum uric acid,serum IgA,Complement C3,24-hour urinary protein:renal biopsy is the criteria for diagnosis.So far,there is a lack of uniform scoring system to assess renal lesion. |
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| ISSN: | 1671-2390 |