Immunological microenvironment and targeted therapeutics in multiple sclerosis: new insights in crosstalk between immune niches and CNS

Immunological microenvironment and targeted therapeutics in multiple sclerosis: new insights in crosstalk between immune niches and CNS

Multiple sclerosis (MS) is a chronic autoimmune disorder of the central nervous system (CNS) that predominantly affects young adults. However, current disease-modifying therapies demonstrate limited efficacy in addressing progressive disease subtypes, underscoring the urgent need for novel therapeut...

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Bibliographic Details
Main Authors: Xiaodi Sun, Feng Zhang, Luojinyun Wang, Gyeore Lee, Sibo Yang, Daqiang Zhou, Bohao Chang, Bo Hu, Yifan Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
multiple sclerosis
autoimmune
neuroimmune
cerebral immune niches
targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1604987/full
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