Copy number signature analysis tool and its application in prostate cancer reveals distinct mutational processes and clinical outcomes.
Genome alteration signatures reflect recurring patterns caused by distinct endogenous or exogenous mutational events during the evolution of cancer. Signatures of single base substitution (SBS) have been extensively studied in different types of cancer. Copy number alterations are important drivers...
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| Main Authors: | Shixiang Wang, Huimin Li, Minfang Song, Ziyu Tao, Tao Wu, Zaoke He, Xiangyu Zhao, Kai Wu, Xue-Song Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-05-01
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| Series: | PLoS Genetics |
| Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1009557&type=printable |
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