Clear cell adenocarcinoma of the male urethra: clinical case report

Primary clear cell adenocarcinoma of the urethra is a rare malignancy and most of the cases described are in women. The symptomatology is similar to other tumors of the urethra. Because it is a rare malignancy and the consequent lack of trials in the medical literature, there is no data about the mo...

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Main Authors: Juliana Sinezio Santos, Gabriella Oliveira Mendes, Fernando Sabino Marques Monteiro
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2021-10-01
Series:Brazilian Journal of Oncology
Subjects:
Online Access:http://www.brazilianjournalofoncology.com.br/details/149/en-US/clear-cell-adenocarcinoma-of-the-male-urethra--clinical-case-report
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author Juliana Sinezio Santos
Gabriella Oliveira Mendes
Fernando Sabino Marques Monteiro
author_facet Juliana Sinezio Santos
Gabriella Oliveira Mendes
Fernando Sabino Marques Monteiro
author_sort Juliana Sinezio Santos
collection DOAJ
description Primary clear cell adenocarcinoma of the urethra is a rare malignancy and most of the cases described are in women. The symptomatology is similar to other tumors of the urethra. Because it is a rare malignancy and the consequent lack of trials in the medical literature, there is no data about the most appropriate treatment for this disease. We aim to describe a clinical case of primary clear cell adenocarcinoma of the urethra in a young male patient. This is a 36-year-old male diagnosed with primary clear cell adenocarcinoma of the urethra whom underwent a surgery for localized disease and about 30 months later he had a local and systemic recurrence. He was treated with platinum-based chemotherapy and presented an excellent clinical and radiological response. Although there is no optimal treatment for this malignancy, in the case of metastatic disease, systemic platinum-based chemotherapy should be considered an appropriate option.
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publisher Thieme Revinter Publicações Ltda.
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series Brazilian Journal of Oncology
spelling doaj-art-1e5cd2f744c942ff8ded2f9ad09a64422025-08-20T03:17:48ZengThieme Revinter Publicações Ltda.Brazilian Journal of Oncology2526-87322021-10-01170010.5935/2526-8732.20210007Clear cell adenocarcinoma of the male urethra: clinical case reportJuliana Sinezio Santos0https://orcid.org/0000-0003-3426-2167Gabriella Oliveira Mendes1Fernando Sabino Marques Monteiro2Hospital Santa Lucia, Oncology Department - Brasília - Distrito Federal - BrazilHospital Santa Lucia, Oncology Department - Brasília - Distrito Federal - BrazilHospital Santa Lucia, Oncology Department - Brasília - Distrito Federal - BrazilPrimary clear cell adenocarcinoma of the urethra is a rare malignancy and most of the cases described are in women. The symptomatology is similar to other tumors of the urethra. Because it is a rare malignancy and the consequent lack of trials in the medical literature, there is no data about the most appropriate treatment for this disease. We aim to describe a clinical case of primary clear cell adenocarcinoma of the urethra in a young male patient. This is a 36-year-old male diagnosed with primary clear cell adenocarcinoma of the urethra whom underwent a surgery for localized disease and about 30 months later he had a local and systemic recurrence. He was treated with platinum-based chemotherapy and presented an excellent clinical and radiological response. Although there is no optimal treatment for this malignancy, in the case of metastatic disease, systemic platinum-based chemotherapy should be considered an appropriate option.http://www.brazilianjournalofoncology.com.br/details/149/en-US/clear-cell-adenocarcinoma-of-the-male-urethra--clinical-case-reportadenocarcinomaclear cellurethral neoplasmsmale urogenital diseasessystemic management
spellingShingle Juliana Sinezio Santos
Gabriella Oliveira Mendes
Fernando Sabino Marques Monteiro
Clear cell adenocarcinoma of the male urethra: clinical case report
Brazilian Journal of Oncology
adenocarcinoma
clear cell
urethral neoplasms
male urogenital diseases
systemic management
title Clear cell adenocarcinoma of the male urethra: clinical case report
title_full Clear cell adenocarcinoma of the male urethra: clinical case report
title_fullStr Clear cell adenocarcinoma of the male urethra: clinical case report
title_full_unstemmed Clear cell adenocarcinoma of the male urethra: clinical case report
title_short Clear cell adenocarcinoma of the male urethra: clinical case report
title_sort clear cell adenocarcinoma of the male urethra clinical case report
topic adenocarcinoma
clear cell
urethral neoplasms
male urogenital diseases
systemic management
url http://www.brazilianjournalofoncology.com.br/details/149/en-US/clear-cell-adenocarcinoma-of-the-male-urethra--clinical-case-report
work_keys_str_mv AT julianasineziosantos clearcelladenocarcinomaofthemaleurethraclinicalcasereport
AT gabriellaoliveiramendes clearcelladenocarcinomaofthemaleurethraclinicalcasereport
AT fernandosabinomarquesmonteiro clearcelladenocarcinomaofthemaleurethraclinicalcasereport