Gut microbiome diversity as adjuvant marker for immune function
The gastrointestinal (GI) tract represents our most intimate contact with the external environment. The GI tract responsible for extracting the appropriate nutrients we need to thrive, maintaining an appropriate balance of helpful and harmful microbes, and acting as a conduit for waste removal. In...
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| Format: | Article |
| Language: | English |
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Indonesian Society for Biochemistry and Molecular Biology
2022-06-01
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| Series: | Acta Biochimica Indonesiana |
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| Online Access: | https://pbbmi.org/newjurnal/index.php/actabioina/article/view/80 |
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| _version_ | 1825199554460385280 |
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| author | Mahdaleny Febriana Catur Iswanti |
| author_facet | Mahdaleny Febriana Catur Iswanti |
| author_sort | Mahdaleny |
| collection | DOAJ |
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The gastrointestinal (GI) tract represents our most intimate contact with the external environment. The GI tract responsible for extracting the appropriate nutrients we need to thrive, maintaining an appropriate balance of helpful and harmful microbes, and acting as a conduit for waste removal. In essence, the extracellular matrix of gut mucosal biofilm is a complex network of microbes and their secretions, as well as the host's secretions and signals (mainly mucus/mucin). Mucin, bacterial polysaccharides, and protein combine to form a unique mucosal biofilm that serves as a home for a variety of commensal and pathogenic organisms in the host. Maintaining proper mucosal barrier function is vital for both GI and systemic health. The lumen of the gut contains numerous entities that should never reach the bloodstream or lymphatic system. The mucosal barrier's integrity is maintained by a single layer of tightly fitted columnar epithelial, and more than 70% of the immune system components are closely associated with the GI tract.
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| format | Article |
| id | doaj-art-1e5ccd8b0f6549f39828cef3c07d0171 |
| institution | Kabale University |
| issn | 2654-6108 2654-3222 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Indonesian Society for Biochemistry and Molecular Biology |
| record_format | Article |
| series | Acta Biochimica Indonesiana |
| spelling | doaj-art-1e5ccd8b0f6549f39828cef3c07d01712025-02-08T03:06:03ZengIndonesian Society for Biochemistry and Molecular BiologyActa Biochimica Indonesiana2654-61082654-32222022-06-015110.32889/actabioina.80Gut microbiome diversity as adjuvant marker for immune functionMahdaleny0Febriana Catur Iswanti1Master's Programme in Biomedical Sciences Faculty of Medicine Universitas IndonesiaDepartement of Biochemistry and Molecular Biology, Faculty of Medicine, Universitas Indonesia, Jakarta 10430 The gastrointestinal (GI) tract represents our most intimate contact with the external environment. The GI tract responsible for extracting the appropriate nutrients we need to thrive, maintaining an appropriate balance of helpful and harmful microbes, and acting as a conduit for waste removal. In essence, the extracellular matrix of gut mucosal biofilm is a complex network of microbes and their secretions, as well as the host's secretions and signals (mainly mucus/mucin). Mucin, bacterial polysaccharides, and protein combine to form a unique mucosal biofilm that serves as a home for a variety of commensal and pathogenic organisms in the host. Maintaining proper mucosal barrier function is vital for both GI and systemic health. The lumen of the gut contains numerous entities that should never reach the bloodstream or lymphatic system. The mucosal barrier's integrity is maintained by a single layer of tightly fitted columnar epithelial, and more than 70% of the immune system components are closely associated with the GI tract. https://pbbmi.org/newjurnal/index.php/actabioina/article/view/80gastrointestinal tractbiofilmsextracellular matrixbiopsymucins |
| spellingShingle | Mahdaleny Febriana Catur Iswanti Gut microbiome diversity as adjuvant marker for immune function Acta Biochimica Indonesiana gastrointestinal tract biofilms extracellular matrix biopsy mucins |
| title | Gut microbiome diversity as adjuvant marker for immune function |
| title_full | Gut microbiome diversity as adjuvant marker for immune function |
| title_fullStr | Gut microbiome diversity as adjuvant marker for immune function |
| title_full_unstemmed | Gut microbiome diversity as adjuvant marker for immune function |
| title_short | Gut microbiome diversity as adjuvant marker for immune function |
| title_sort | gut microbiome diversity as adjuvant marker for immune function |
| topic | gastrointestinal tract biofilms extracellular matrix biopsy mucins |
| url | https://pbbmi.org/newjurnal/index.php/actabioina/article/view/80 |
| work_keys_str_mv | AT mahdaleny gutmicrobiomediversityasadjuvantmarkerforimmunefunction AT febrianacaturiswanti gutmicrobiomediversityasadjuvantmarkerforimmunefunction |