Nicotinamide Counteracts Ultraviolet-B-Induced Cytotoxic Effects and Aquaporins Overexpression in the A375 Melanoma Cell Line

Nicotinamide Counteracts Ultraviolet-B-Induced Cytotoxic Effects and Aquaporins Overexpression in the A375 Melanoma Cell Line

Background/objectives: Ultraviolet-B (UVB) represents a major extrinsic factor in skin cancer development, causing cellular changes that are not yet fully understood. Aquaporins (AQPs) are a family of transmembrane proteins that favor water transport and are involved in several pathways. Nicotinamid...

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Bibliographic Details
Main Authors: Lara Camillo, Elia Esposto, Laura Cristina Gironi, Elisa Zavattaro, Paola Savoia
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Dermato
Subjects:
aquaporins
melanoma
UVB radiation
nicotinamide
vitamin B3
DNA damage
Online Access:https://www.mdpi.com/2673-6179/5/1/3
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