Genetic alterations affect immune contexture of non-small cell lung cancer: Ukrainian study

Genetic alterations affect immune contexture of non-small cell lung cancer: Ukrainian study

IntroductionAlthough the role of various genetic alterations was highlighted among factors affecting the response to immunotherapy in non-small cell lung cancer (NSCLC), the relations between oncogenic driver variants and changes in the cancer immunity cycle are still unclear.AimThe study aimed to d...

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Main Authors: Denys Kozakov, Nazarii Kobyliak, Sofiia Livshun, Oleksii Seleznov, Olena Koshyk, Alina Matvieieva, Yaroslav Shparyk, Oleksii Kolesnik, Yuliia Moskalenko, Oleksandr Vynnychenko, Roman Moskalenko, Serhii Kropyvko, Anna Khmel, Bogdana Shkarupii, Oksana Sulaieva
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Medicine
Subjects:
non-small cell lung cancer
adenocarcinoma
genetic alterations
oncogenes
immune contexture
cancer immunity cycle
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1558016/full
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