Antimicrobial stewardship approach: Prevalence of antimicrobial resistant bacteria at a regional hospital in South Africa
Introduction: Antimicrobial stewardship practices are crucial for the regular surveillance to change the antimicrobial policy. This study was conducted to decide the prevalence of common bacteria and their antibiogram regarding antimicrobial stewardship program within one year, at the regional and...
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The Journal of Infection in Developing Countries
2019-08-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/10685 |
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| author | Khin SL Han Lopez Gustavo Venesh C Rajkumar Khine Swe Swe-Han |
| author_facet | Khin SL Han Lopez Gustavo Venesh C Rajkumar Khine Swe Swe-Han |
| author_sort | Khin SL Han |
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Introduction: Antimicrobial stewardship practices are crucial for the regular surveillance to change the antimicrobial policy. This study was conducted to decide the prevalence of common bacteria and their antibiogram regarding antimicrobial stewardship program within one year, at the regional and district, Stanger hospital in South Africa.
Methodology: It was based the study on clinical data and laboratory records of the patients. It reviewed the clinical and laboratory data. The prevalence/proportion rate was calculated and correlated with the majority of microorganism vs empirical therapy.
Results: The prevalence of MRSA, MRSE, VRSA, ESBL+ K. pneumoniae; E. coli cultured from the blood was 25%, 49%, 2%, 62% and 27% respectively. Similarly, we analysed for other targeted MDROs organisms (Acinetobacter species and P. aeruginosa, CRE, CPE) isolated from blood culture and endotracheal aspirate. The prevalence of MDR Acinetobacter species exceeded 61%, 33% from the blood and ETA respectively. The prevalence of MDR P. aeruginosa was 10% from ETA. The MRSA, MRSE, VRSA, VRE were observed in blood specimen. The majority of the microorganisms cultured from the CSF was Cryptococcus neoformans and followed by bacteria: Streptococcus pneumonia, Streptococcus group B and Haemorphilus influenza.
Conclusion: The selection of empirical antimicrobial therapy relates not only the institutions or unit-specific antibiogram but also the site of infection. We can further suggest continuing to do surveillance of antibiogram and prevalence of MDR organisms for infection control as well as for empirical therapy, part of the antimicrobial stewardship program based on yearly records to change the local hospital antibiotic policy.
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| format | Article |
| id | doaj-art-1e2a96527fd948ec920d10da88bf79e9 |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2019-08-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-1e2a96527fd948ec920d10da88bf79e92025-08-20T02:14:07ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802019-08-01130810.3855/jidc.10685Antimicrobial stewardship approach: Prevalence of antimicrobial resistant bacteria at a regional hospital in South AfricaKhin SL Han0Lopez Gustavo1Venesh C Rajkumar2Khine Swe Swe-Han3Intensive care unit, Stanger Hospital, Stanger, South AfricaIntensive care unit, Stanger Hospital, Stanger, South AfricaIlembe Health District, Stanger Hospital, Kwa-Dukuza, Stanger, South AfricaNational Health Laboratory Service, Durban, South Africa Introduction: Antimicrobial stewardship practices are crucial for the regular surveillance to change the antimicrobial policy. This study was conducted to decide the prevalence of common bacteria and their antibiogram regarding antimicrobial stewardship program within one year, at the regional and district, Stanger hospital in South Africa. Methodology: It was based the study on clinical data and laboratory records of the patients. It reviewed the clinical and laboratory data. The prevalence/proportion rate was calculated and correlated with the majority of microorganism vs empirical therapy. Results: The prevalence of MRSA, MRSE, VRSA, ESBL+ K. pneumoniae; E. coli cultured from the blood was 25%, 49%, 2%, 62% and 27% respectively. Similarly, we analysed for other targeted MDROs organisms (Acinetobacter species and P. aeruginosa, CRE, CPE) isolated from blood culture and endotracheal aspirate. The prevalence of MDR Acinetobacter species exceeded 61%, 33% from the blood and ETA respectively. The prevalence of MDR P. aeruginosa was 10% from ETA. The MRSA, MRSE, VRSA, VRE were observed in blood specimen. The majority of the microorganisms cultured from the CSF was Cryptococcus neoformans and followed by bacteria: Streptococcus pneumonia, Streptococcus group B and Haemorphilus influenza. Conclusion: The selection of empirical antimicrobial therapy relates not only the institutions or unit-specific antibiogram but also the site of infection. We can further suggest continuing to do surveillance of antibiogram and prevalence of MDR organisms for infection control as well as for empirical therapy, part of the antimicrobial stewardship program based on yearly records to change the local hospital antibiotic policy. https://jidc.org/index.php/journal/article/view/10685prevalencesurveillanceantimicrobial resistant bacteriaempirical therapyantibiotic stewardship program |
| spellingShingle | Khin SL Han Lopez Gustavo Venesh C Rajkumar Khine Swe Swe-Han Antimicrobial stewardship approach: Prevalence of antimicrobial resistant bacteria at a regional hospital in South Africa Journal of Infection in Developing Countries prevalence surveillance antimicrobial resistant bacteria empirical therapy antibiotic stewardship program |
| title | Antimicrobial stewardship approach: Prevalence of antimicrobial resistant bacteria at a regional hospital in South Africa |
| title_full | Antimicrobial stewardship approach: Prevalence of antimicrobial resistant bacteria at a regional hospital in South Africa |
| title_fullStr | Antimicrobial stewardship approach: Prevalence of antimicrobial resistant bacteria at a regional hospital in South Africa |
| title_full_unstemmed | Antimicrobial stewardship approach: Prevalence of antimicrobial resistant bacteria at a regional hospital in South Africa |
| title_short | Antimicrobial stewardship approach: Prevalence of antimicrobial resistant bacteria at a regional hospital in South Africa |
| title_sort | antimicrobial stewardship approach prevalence of antimicrobial resistant bacteria at a regional hospital in south africa |
| topic | prevalence surveillance antimicrobial resistant bacteria empirical therapy antibiotic stewardship program |
| url | https://jidc.org/index.php/journal/article/view/10685 |
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