Prescribing Patterns of Antibiotics in Pediatric Wards of Secondary Care Centers: A Retrospective Study Based on WHO AWaRe Classification

Prescribing Patterns of Antibiotics in Pediatric Wards of Secondary Care Centers: A Retrospective Study Based on WHO AWaRe Classification

Objectives. Antimicrobial resistance (AMR) poses a significant threat to global public health, with substantial mortality rates attributed to AMR-related infections. Pediatric populations face heightened vulnerability due to prevalent antimicrobial misuse. This study aimed at addressing the signific...

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Main Authors: Afia Tariq Butt MBBS, FCPS, Sobia Ramzan MBBS, FCPS, Dania Shabbir MBBS, Amna Sajjad MBBS, FCPS, Murk Shaikh MBBS, FCPS, Maryam Iqbal Syed MBBS, FCPS, Mohammad Aadil Qamar MBBS
Format: Article
Language:English
Published: SAGE Publishing 2024-10-01
Series:Global Pediatric Health
Online Access:https://doi.org/10.1177/2333794X241291409
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Summary:Objectives. Antimicrobial resistance (AMR) poses a significant threat to global public health, with substantial mortality rates attributed to AMR-related infections. Pediatric populations face heightened vulnerability due to prevalent antimicrobial misuse. This study aimed at addressing the significant threat of antimicrobial resistance (AMR) and its associated mortality rates. Methods . This retrospective cross-sectional multicentric study investigated antibiotic prescribing patterns in pediatric wards of 4 secondary care hospitals affiliated with Aga Khan University Hospital. The study utilized the WHO Access, Watch, and Reserve (AWaRe) classification framework. Data from 6934 encounters were analyzed. Results . Antibiotics were prescribed in 78.1% of encounters, with intravenous administration being predominant (98.6%). Ceftriaxone was the most prescribed antibiotic agent (45.8%), and third-generation cephalosporins constituted the most prevalent antibiotic class (54.4%). Pneumonia exhibited the highest prescription rate (99.9%), with Watch group antibiotics being predominantly prescribed (>80%) across hospitals. Conclusion . These findings underscore the urgency for targeted interventions to optimize prescribing practices and mitigate resistance.
ISSN:2333-794X

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