Role of Biochemical Inflammatory Markers in Patients with Chemotherapy-Induced Neutropenia
The growing number of autologous and allogeneic transplantations of bone marrow and hematopoietic stem cells as well as their technological effectiveness give rise to drug antineoplastic therapies with increased toxicity leading to development of complications. The most serious among this sort of co...
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| Format: | Article |
| Language: | Russian |
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Practical Medicine Publishing House
2019-09-01
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| Series: | Клиническая онкогематология |
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http://bloodjournal.ru/wp-content/uploads/2019/09/12-1.pdf
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| author | YuN Dubinina VO Sarzhevskii VYa Melnichenko |
| author_facet | YuN Dubinina VO Sarzhevskii VYa Melnichenko |
| author_sort | YuN Dubinina |
| collection | DOAJ |
| description | The growing number of autologous and allogeneic transplantations of bone marrow and hematopoietic stem cells as well as their technological effectiveness give rise to drug antineoplastic therapies with increased toxicity leading to development of complications. The most serious among this sort of complications are infections. Probability of infections in patients with chemotherapy-induced neutropenia reaches 90 %. In this context the search for an optimal marker of infectious complications becomes more and more important. The present review deals with basic biochemical inflammatory markers and the analysis of trials assessing diagnostic and prognostic value of C-reactive protein, procalcitonin, and presepsin. |
| format | Article |
| id | doaj-art-1e235d3fc3604c0f8a93682c32e4df97 |
| institution | Kabale University |
| issn | 1997-6933 2500-2139 |
| language | Russian |
| publishDate | 2019-09-01 |
| publisher | Practical Medicine Publishing House |
| record_format | Article |
| series | Клиническая онкогематология |
| spelling | doaj-art-1e235d3fc3604c0f8a93682c32e4df972025-08-20T03:54:33ZrusPractical Medicine Publishing HouseКлиническая онкогематология1997-69332500-21392019-09-0112446146710.21320/2500-2139-2019-12-4-461-46719976933Role of Biochemical Inflammatory Markers in Patients with Chemotherapy-Induced NeutropeniaYuN Dubinina0VO Sarzhevskii1VYa Melnichenko2 Oncology and Hematology Outpatient Clinic, 2 bld. 1 Molodogvardeiskaya str., Moscow, Russian Federation, 121467 NI Pirogov Russian National Medical Center of Surgery, 70 Nizhnyaya Pervomaiskaya str., Moscow, Russian Federation, 105203 NI Pirogov Russian National Medical Center of Surgery, 70 Nizhnyaya Pervomaiskaya str., Moscow, Russian Federation, 105203 The growing number of autologous and allogeneic transplantations of bone marrow and hematopoietic stem cells as well as their technological effectiveness give rise to drug antineoplastic therapies with increased toxicity leading to development of complications. The most serious among this sort of complications are infections. Probability of infections in patients with chemotherapy-induced neutropenia reaches 90 %. In this context the search for an optimal marker of infectious complications becomes more and more important. The present review deals with basic biochemical inflammatory markers and the analysis of trials assessing diagnostic and prognostic value of C-reactive protein, procalcitonin, and presepsin. http://bloodjournal.ru/wp-content/uploads/2019/09/12-1.pdf sepsisautologous bone marrow transplantationallogeneic bone marrow transplantationchemotherapyinfectionprocalcitoninpresepsinc-reactive protein |
| spellingShingle | YuN Dubinina VO Sarzhevskii VYa Melnichenko Role of Biochemical Inflammatory Markers in Patients with Chemotherapy-Induced Neutropenia Клиническая онкогематология sepsis autologous bone marrow transplantation allogeneic bone marrow transplantation chemotherapy infection procalcitonin presepsin c-reactive protein |
| title | Role of Biochemical Inflammatory Markers in Patients with Chemotherapy-Induced Neutropenia |
| title_full | Role of Biochemical Inflammatory Markers in Patients with Chemotherapy-Induced Neutropenia |
| title_fullStr | Role of Biochemical Inflammatory Markers in Patients with Chemotherapy-Induced Neutropenia |
| title_full_unstemmed | Role of Biochemical Inflammatory Markers in Patients with Chemotherapy-Induced Neutropenia |
| title_short | Role of Biochemical Inflammatory Markers in Patients with Chemotherapy-Induced Neutropenia |
| title_sort | role of biochemical inflammatory markers in patients with chemotherapy induced neutropenia |
| topic | sepsis autologous bone marrow transplantation allogeneic bone marrow transplantation chemotherapy infection procalcitonin presepsin c-reactive protein |
| url |
http://bloodjournal.ru/wp-content/uploads/2019/09/12-1.pdf
|
| work_keys_str_mv | AT yundubinina roleofbiochemicalinflammatorymarkersinpatientswithchemotherapyinducedneutropenia AT vosarzhevskii roleofbiochemicalinflammatorymarkersinpatientswithchemotherapyinducedneutropenia AT vyamelnichenko roleofbiochemicalinflammatorymarkersinpatientswithchemotherapyinducedneutropenia |