The inflammatory endotype in osteoarthritis: Reflections from the 2024 OARSI clinical trials symposium (CTS) with a special emphasis on feasibility for clinical developmentBiomarkers of high value

The inflammatory endotype in osteoarthritis: Reflections from the 2024 OARSI clinical trials symposium (CTS) with a special emphasis on feasibility for clinical developmentBiomarkers of high value

Objective: The inflammatory endotype is arguably one of the most well-established endotype in osteoarthritis (OA). While endotyping holds promise for advancing drug development, numerous potential challenges must be considered, addressed and resolved before successful clinical outcomes can be achiev...

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Bibliographic Details
Main Authors: Morten Asser Karsdal, Lucio C. Rovati, Jeyanesh Tambiah, Olga Kubassova, Christoph Ladel, Francis Berenbaum, Anne-Christine Bay-Jensen, Lachy Mclean, Richard Loeser, Ali Mobasheri, Virginia B. Kraus
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Osteoarthritis and Cartilage Open
Subjects:
Osteoarthritis
Stratification
Clinical development
Inflammation
Phenotype
Endotype
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913125000081
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