Deciphering the pharmacological mechanism of Radix astragali for allergic rhinitis through network pharmacology and experimental validation

Deciphering the pharmacological mechanism of Radix astragali for allergic rhinitis through network pharmacology and experimental validation

Abstract Radix Astragali (RA) has been recognized for its therapeutic potential in allergic rhinitis (AR), yet its potential pharmacological mechanisms remain elusive. This study systematically investigated the physicochemical properties and biological activities of RA’s phytochemicals, aiming to el...

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Bibliographic Details
Main Authors: Yiwei Hua, Xi Tan, Jingwen Zhang, Ningcong Xu, Ruien Chen, Shiqing Zhou, Shaoqing Liu, Kai Li, Wenyong Chen, Qiulan Luo, Yunying Li
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Radix astragali
Allergic rhinitis
Network pharmacology
Molecular docking and dynamics
Online Access:https://doi.org/10.1038/s41598-024-80101-1
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