Direct Measurement of the Ciliary Sulcus Diameter Using Optical Coherence Tomography—Inter-Rater Variability

The determination of sulcus-to-sulcus measurements has been challenging due to the limitations of current approaches. Ultrasound methods are highly operator-dependent and require extensive training, while traditional optical devices cannot visualize structures posterior to the iris. However, modern...

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Main Authors: Timo Eppig, Manuel Seer, Antonio Martinez-Abad, Virgilio Galvis, Saskia Schütz, Alejandro Tello, Michiel C. Rombach, Jorge L. Alió
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Sensors
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Online Access:https://www.mdpi.com/1424-8220/24/21/6950
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author Timo Eppig
Manuel Seer
Antonio Martinez-Abad
Virgilio Galvis
Saskia Schütz
Alejandro Tello
Michiel C. Rombach
Jorge L. Alió
author_facet Timo Eppig
Manuel Seer
Antonio Martinez-Abad
Virgilio Galvis
Saskia Schütz
Alejandro Tello
Michiel C. Rombach
Jorge L. Alió
author_sort Timo Eppig
collection DOAJ
description The determination of sulcus-to-sulcus measurements has been challenging due to the limitations of current approaches. Ultrasound methods are highly operator-dependent and require extensive training, while traditional optical devices cannot visualize structures posterior to the iris. However, modern optical anterior segment coherence tomography (AS-OCT) devices are changing this paradigm by identifying some anatomical landmarks posterior to the iris. This study evaluates the reproducibility of optical sulcus measurements in the context of sizing a novel accommodative intraocular lens (IOL). Preoperative OCT scans of patients scheduled for cataract surgery were analyzed regarding the dimensions of the ciliary sulcus using a custom scan method with a clinically available anterior segment optical coherence tomographer. Measurements were compared between two different readers, and various derived parameters were compared. The measurements by both readers were highly correlated (R<sup>2</sup> > 0.96), and their agreement was excellent (mean difference 0.02 mm with 95% limits of agreement from −0.11 to 0.15 mm). In contrast, the sulcus diameter measurement did not agree well with automatically calculated values, such as the anterior chamber width or white-to-white. This leads to the conclusion that modern swept-source AS-OCT measurements of the ciliary sulcus dimensions are feasible, reproducible, and may be a clinically useful tool.
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spelling doaj-art-1e1f13b020df47938f29738bc3f933642025-08-20T02:14:23ZengMDPI AGSensors1424-82202024-10-012421695010.3390/s24216950Direct Measurement of the Ciliary Sulcus Diameter Using Optical Coherence Tomography—Inter-Rater VariabilityTimo Eppig0Manuel Seer1Antonio Martinez-Abad2Virgilio Galvis3Saskia Schütz4Alejandro Tello5Michiel C. Rombach6Jorge L. Alió7Institute of Experimental Ophthalmology, Saarland University, 66421 Homburg, GermanyAMIPLANT GmbH, 91220 Schnaittach, GermanyVissum Grupo Miranza, 03016 Alicante, SpainCentro Oftalmologico Virgilio Galvis, Floridablanca 681004, ColombiaAMIPLANT GmbH, 91220 Schnaittach, GermanyCentro Oftalmologico Virgilio Galvis, Floridablanca 681004, ColombiaAKKOLENS International b.v., 4836 BA Breda, The NetherlandsVissum Grupo Miranza, 03016 Alicante, SpainThe determination of sulcus-to-sulcus measurements has been challenging due to the limitations of current approaches. Ultrasound methods are highly operator-dependent and require extensive training, while traditional optical devices cannot visualize structures posterior to the iris. However, modern optical anterior segment coherence tomography (AS-OCT) devices are changing this paradigm by identifying some anatomical landmarks posterior to the iris. This study evaluates the reproducibility of optical sulcus measurements in the context of sizing a novel accommodative intraocular lens (IOL). Preoperative OCT scans of patients scheduled for cataract surgery were analyzed regarding the dimensions of the ciliary sulcus using a custom scan method with a clinically available anterior segment optical coherence tomographer. Measurements were compared between two different readers, and various derived parameters were compared. The measurements by both readers were highly correlated (R<sup>2</sup> > 0.96), and their agreement was excellent (mean difference 0.02 mm with 95% limits of agreement from −0.11 to 0.15 mm). In contrast, the sulcus diameter measurement did not agree well with automatically calculated values, such as the anterior chamber width or white-to-white. This leads to the conclusion that modern swept-source AS-OCT measurements of the ciliary sulcus dimensions are feasible, reproducible, and may be a clinically useful tool.https://www.mdpi.com/1424-8220/24/21/6950ocular dimensionsoptical coherence tomographyintraocular lens
spellingShingle Timo Eppig
Manuel Seer
Antonio Martinez-Abad
Virgilio Galvis
Saskia Schütz
Alejandro Tello
Michiel C. Rombach
Jorge L. Alió
Direct Measurement of the Ciliary Sulcus Diameter Using Optical Coherence Tomography—Inter-Rater Variability
Sensors
ocular dimensions
optical coherence tomography
intraocular lens
title Direct Measurement of the Ciliary Sulcus Diameter Using Optical Coherence Tomography—Inter-Rater Variability
title_full Direct Measurement of the Ciliary Sulcus Diameter Using Optical Coherence Tomography—Inter-Rater Variability
title_fullStr Direct Measurement of the Ciliary Sulcus Diameter Using Optical Coherence Tomography—Inter-Rater Variability
title_full_unstemmed Direct Measurement of the Ciliary Sulcus Diameter Using Optical Coherence Tomography—Inter-Rater Variability
title_short Direct Measurement of the Ciliary Sulcus Diameter Using Optical Coherence Tomography—Inter-Rater Variability
title_sort direct measurement of the ciliary sulcus diameter using optical coherence tomography inter rater variability
topic ocular dimensions
optical coherence tomography
intraocular lens
url https://www.mdpi.com/1424-8220/24/21/6950
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