MLKL is involved in the regulation of skin wound healing and interplay between macrophages and myofibroblasts in mice

MLKL is involved in the regulation of skin wound healing and interplay between macrophages and myofibroblasts in mice

Abstract Mixed lineage kinase domain-like protein (MLKL), a critical necroptosis effector, is strongly linked to inflammation, a key component of skin wound healing. However, its precise role in the wound healing process remains inadequately characterized. This study revealed sustained MLKL overexpr...

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Bibliographic Details
Main Authors: Jiamin Zhao, Shuangyi Zhang, Yunjie Bai, Zhiguo Gong, Wenhui Bao, Zhuoya Yu, Bo Liu, Wei Mao, Surong Hasi
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Skin
Wound healing
MLKL
Macrophages
Myofibroblasts
Online Access:https://doi.org/10.1038/s41598-025-97729-2
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