Taurine corrects lupus CD4+ T cell imbalance through inhibition of mTORC1 signaling

Taurine corrects lupus CD4+ T cell imbalance through inhibition of mTORC1 signaling

Abstract Objective This study was designed to explore the metabolism features in systemic lupus erythematosus (SLE) and to investigate the role and regulatory mechanism of taurine in the control of CD4+ T cells and the progression of SLE. Methods Metabolomic profiles of sera from SLE patients and he...

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Bibliographic Details
Main Authors: Saisai Huang, Yiyuan Cui, Yaqi Zhang, Hanyin Deng, Shanshan Liu, Xuebing Feng
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Nutrition & Metabolism
Subjects:
Taurine
Metabolism
CD4+ T cell
mTOR
Systemic lupus erythematosus
Online Access:https://doi.org/10.1186/s12986-025-00936-x
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