Unusual Clinical Presentations and Diagnostic Challenges of Pediatric Ewing’s Sarcoma: A Case Series from a Tertiary Oncology Center
We present a case series of three pediatric patients diagnosed with Ewing’s sarcoma at distinct anatomical sites—the scalp with intracranial extension, the forearm involving bone, and the lumbar region with metastatic spread. Each patient underwent a detailed clinical assessment, radiological imagi...
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| Format: | Article |
| Language: | English |
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University of Lahore
2025-06-01
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| Series: | Journal of University College of Medicine and Dentistry |
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| Online Access: | https://journals.uol.edu.pk/jucmd/article/view/4025 |
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| author | Ruqayya Manzoor |
| author_facet | Ruqayya Manzoor |
| author_sort | Ruqayya Manzoor |
| collection | DOAJ |
| description |
We present a case series of three pediatric patients diagnosed with Ewing’s sarcoma at distinct anatomical sites—the scalp with intracranial extension, the forearm involving bone, and the lumbar region with metastatic spread. Each patient underwent a detailed clinical assessment, radiological imaging, histopathology, and immunohistochemistry for diagnosis. Treatment comprised a multidisciplinary approach including surgical resection, chemotherapy, and radiotherapy. Our findings highlight the diverse clinical manifestations, diagnostic challenges, and the critical role of early detection and individualized treatment strategies in optimizing outcomes for Ewing’s sarcoma patients.
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| format | Article |
| id | doaj-art-1e0075b8e62842c1bb3fbf5085600747 |
| institution | OA Journals |
| issn | 2790-3443 2790-3451 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | University of Lahore |
| record_format | Article |
| series | Journal of University College of Medicine and Dentistry |
| spelling | doaj-art-1e0075b8e62842c1bb3fbf50856007472025-08-20T02:07:23ZengUniversity of LahoreJournal of University College of Medicine and Dentistry2790-34432790-34512025-06-014210.51846/jucmd.v4i2.4025Unusual Clinical Presentations and Diagnostic Challenges of Pediatric Ewing’s Sarcoma: A Case Series from a Tertiary Oncology CenterRuqayya Manzoor0Assistant Professor, Department of Pediatric Oncology, Children Hospital Pakistan Institute of Medical Sciences, Islamabad, Pakistan We present a case series of three pediatric patients diagnosed with Ewing’s sarcoma at distinct anatomical sites—the scalp with intracranial extension, the forearm involving bone, and the lumbar region with metastatic spread. Each patient underwent a detailed clinical assessment, radiological imaging, histopathology, and immunohistochemistry for diagnosis. Treatment comprised a multidisciplinary approach including surgical resection, chemotherapy, and radiotherapy. Our findings highlight the diverse clinical manifestations, diagnostic challenges, and the critical role of early detection and individualized treatment strategies in optimizing outcomes for Ewing’s sarcoma patients. https://journals.uol.edu.pk/jucmd/article/view/4025Ewing's SarcomaPaediatric Bone TumorIntracranial ExtensionMetastasisHistopathologyImmunohistochemistry |
| spellingShingle | Ruqayya Manzoor Unusual Clinical Presentations and Diagnostic Challenges of Pediatric Ewing’s Sarcoma: A Case Series from a Tertiary Oncology Center Journal of University College of Medicine and Dentistry Ewing's Sarcoma Paediatric Bone Tumor Intracranial Extension Metastasis Histopathology Immunohistochemistry |
| title | Unusual Clinical Presentations and Diagnostic Challenges of Pediatric Ewing’s Sarcoma: A Case Series from a Tertiary Oncology Center |
| title_full | Unusual Clinical Presentations and Diagnostic Challenges of Pediatric Ewing’s Sarcoma: A Case Series from a Tertiary Oncology Center |
| title_fullStr | Unusual Clinical Presentations and Diagnostic Challenges of Pediatric Ewing’s Sarcoma: A Case Series from a Tertiary Oncology Center |
| title_full_unstemmed | Unusual Clinical Presentations and Diagnostic Challenges of Pediatric Ewing’s Sarcoma: A Case Series from a Tertiary Oncology Center |
| title_short | Unusual Clinical Presentations and Diagnostic Challenges of Pediatric Ewing’s Sarcoma: A Case Series from a Tertiary Oncology Center |
| title_sort | unusual clinical presentations and diagnostic challenges of pediatric ewing s sarcoma a case series from a tertiary oncology center |
| topic | Ewing's Sarcoma Paediatric Bone Tumor Intracranial Extension Metastasis Histopathology Immunohistochemistry |
| url | https://journals.uol.edu.pk/jucmd/article/view/4025 |
| work_keys_str_mv | AT ruqayyamanzoor unusualclinicalpresentationsanddiagnosticchallengesofpediatricewingssarcomaacaseseriesfromatertiaryoncologycenter |