Early and Late Infections in Newborns: Where Do We Stand? A Review

Neonatal sepsis still represents an important cause of mortality and morbidity among infants. According to the onset, we can distinguish “early onset sepsis” when microbiological cultures positive for external pathogens come from newborns during the first 7 days of life (maternal intrapartum transmi...

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Main Authors: Francesca Cortese, Pietro Scicchitano, Michele Gesualdo, Antonella Filaninno, Elsa De Giorgi, Federico Schettini, Nicola Laforgia, Marco Matteo Ciccone
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Pediatrics and Neonatology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1875957215001758
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author Francesca Cortese
Pietro Scicchitano
Michele Gesualdo
Antonella Filaninno
Elsa De Giorgi
Federico Schettini
Nicola Laforgia
Marco Matteo Ciccone
author_facet Francesca Cortese
Pietro Scicchitano
Michele Gesualdo
Antonella Filaninno
Elsa De Giorgi
Federico Schettini
Nicola Laforgia
Marco Matteo Ciccone
author_sort Francesca Cortese
collection DOAJ
description Neonatal sepsis still represents an important cause of mortality and morbidity among infants. According to the onset, we can distinguish “early onset sepsis” when microbiological cultures positive for external pathogens come from newborns during the first 7 days of life (maternal intrapartum transmission); “late onset sepsis” when microbiological cultures positive for external pathogens come from newborns after the first 7 days from delivery (postnatal acquisition). In this review we synthesize the incidence, risk factors, clinical manifestations, and methods of diagnosis and treatment of each type of neonatal infection, in order to better define such a pathological condition which is of great importance in common clinical practice.
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series Pediatrics and Neonatology
spelling doaj-art-1df744a4baf841c19d74aa583d0430552025-08-20T03:09:41ZengElsevierPediatrics and Neonatology1875-95722016-08-0157426527310.1016/j.pedneo.2015.09.007Early and Late Infections in Newborns: Where Do We Stand? A ReviewFrancesca Cortese0Pietro Scicchitano1Michele Gesualdo2Antonella Filaninno3Elsa De Giorgi4Federico Schettini5Nicola Laforgia6Marco Matteo Ciccone7Cardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO) University of Bari, Bari, ItalyCardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO) University of Bari, Bari, ItalyCardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO) University of Bari, Bari, ItalyNeonatology and NICU Section, Department of Biomedical Sciences and Human Oncology (DIMO) University of Bari, Bari, ItalyNeonatology and NICU Section, Department of Biomedical Sciences and Human Oncology (DIMO) University of Bari, Bari, ItalyNeonatology and NICU Section, Department of Biomedical Sciences and Human Oncology (DIMO) University of Bari, Bari, ItalyNeonatology and NICU Section, Department of Biomedical Sciences and Human Oncology (DIMO) University of Bari, Bari, ItalyCardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO) University of Bari, Bari, ItalyNeonatal sepsis still represents an important cause of mortality and morbidity among infants. According to the onset, we can distinguish “early onset sepsis” when microbiological cultures positive for external pathogens come from newborns during the first 7 days of life (maternal intrapartum transmission); “late onset sepsis” when microbiological cultures positive for external pathogens come from newborns after the first 7 days from delivery (postnatal acquisition). In this review we synthesize the incidence, risk factors, clinical manifestations, and methods of diagnosis and treatment of each type of neonatal infection, in order to better define such a pathological condition which is of great importance in common clinical practice.http://www.sciencedirect.com/science/article/pii/S1875957215001758early onset sepsislate onset sepsisnewborns
spellingShingle Francesca Cortese
Pietro Scicchitano
Michele Gesualdo
Antonella Filaninno
Elsa De Giorgi
Federico Schettini
Nicola Laforgia
Marco Matteo Ciccone
Early and Late Infections in Newborns: Where Do We Stand? A Review
Pediatrics and Neonatology
early onset sepsis
late onset sepsis
newborns
title Early and Late Infections in Newborns: Where Do We Stand? A Review
title_full Early and Late Infections in Newborns: Where Do We Stand? A Review
title_fullStr Early and Late Infections in Newborns: Where Do We Stand? A Review
title_full_unstemmed Early and Late Infections in Newborns: Where Do We Stand? A Review
title_short Early and Late Infections in Newborns: Where Do We Stand? A Review
title_sort early and late infections in newborns where do we stand a review
topic early onset sepsis
late onset sepsis
newborns
url http://www.sciencedirect.com/science/article/pii/S1875957215001758
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