Managing Sleep and Behavioral Problems in a Preschooler with SATB2-Associated Syndrome

SATB2-associated syndrome is an autosomal dominant, multisystemic disorder with associated sleep and behavioral abnormalities. Evidence is limited on appropriate management strategies in this population. We describe the medical management of a four-year-old child with poor sleep and significant beha...

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Main Authors: Nihit Kumar, Yuri A. Zarate
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Genetics
Online Access:http://dx.doi.org/10.1155/2020/8868458
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author Nihit Kumar
Yuri A. Zarate
author_facet Nihit Kumar
Yuri A. Zarate
author_sort Nihit Kumar
collection DOAJ
description SATB2-associated syndrome is an autosomal dominant, multisystemic disorder with associated sleep and behavioral abnormalities. Evidence is limited on appropriate management strategies in this population. We describe the medical management of a four-year-old child with poor sleep and significant behavioral problems. After failing initial treatment with melatonin, we initiated treatment clonidine along with high doses of trazodone for sleep. Daytime treatment with quetiapine was added to successfully manage behavioral issues. We present the challenges associated with treatment strategies in children with this syndrome.
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spelling doaj-art-1def70047a4b4109a6046a3f4ebdb5f22025-08-20T03:54:56ZengWileyCase Reports in Genetics2090-65442090-65522020-01-01202010.1155/2020/88684588868458Managing Sleep and Behavioral Problems in a Preschooler with SATB2-Associated SyndromeNihit Kumar0Yuri A. Zarate1Division of Child & Adolescent Psychiatry, University of Arkansas for Medical Sciences, 4301 W. Markham, Slot 654, Little Rock, AR 72205, USASection of Genetics and Metabolism, University of Arkansas for Medical Sciences, Little Rock, AR, USASATB2-associated syndrome is an autosomal dominant, multisystemic disorder with associated sleep and behavioral abnormalities. Evidence is limited on appropriate management strategies in this population. We describe the medical management of a four-year-old child with poor sleep and significant behavioral problems. After failing initial treatment with melatonin, we initiated treatment clonidine along with high doses of trazodone for sleep. Daytime treatment with quetiapine was added to successfully manage behavioral issues. We present the challenges associated with treatment strategies in children with this syndrome.http://dx.doi.org/10.1155/2020/8868458
spellingShingle Nihit Kumar
Yuri A. Zarate
Managing Sleep and Behavioral Problems in a Preschooler with SATB2-Associated Syndrome
Case Reports in Genetics
title Managing Sleep and Behavioral Problems in a Preschooler with SATB2-Associated Syndrome
title_full Managing Sleep and Behavioral Problems in a Preschooler with SATB2-Associated Syndrome
title_fullStr Managing Sleep and Behavioral Problems in a Preschooler with SATB2-Associated Syndrome
title_full_unstemmed Managing Sleep and Behavioral Problems in a Preschooler with SATB2-Associated Syndrome
title_short Managing Sleep and Behavioral Problems in a Preschooler with SATB2-Associated Syndrome
title_sort managing sleep and behavioral problems in a preschooler with satb2 associated syndrome
url http://dx.doi.org/10.1155/2020/8868458
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