Reversible Renal Insufficiency Secondary to Extrinsic Splenic Compression of the Kidney in a Patient with Chronic Lymphocytic Leukemia

While increased renal venous and direct renal parenchymal pressure may cause renal insufficiency, there are no prior reports of hypersplenism secondary to chronic lymphocytic leukemia (CLL) doing so. This first report of massive splenomegaly leading to marked compression of the left kidney associate...

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Main Authors: Miriam Hadj-Moussa, James A. Brown
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2010.74
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author Miriam Hadj-Moussa
James A. Brown
author_facet Miriam Hadj-Moussa
James A. Brown
author_sort Miriam Hadj-Moussa
collection DOAJ
description While increased renal venous and direct renal parenchymal pressure may cause renal insufficiency, there are no prior reports of hypersplenism secondary to chronic lymphocytic leukemia (CLL) doing so. This first report of massive splenomegaly leading to marked compression of the left kidney associated with renal insufficiency that resolved after splenectomy illustrates that profound extrinsic renal compression from splenomegaly may significantly compromise left renal function and splenectomy should be considered in this situation.
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spelling doaj-art-1def52756dcd4bfbb60881a3508d5c5c2025-08-20T02:01:40ZengWileyThe Scientific World Journal1537-744X2010-01-011079679810.1100/tsw.2010.74Reversible Renal Insufficiency Secondary to Extrinsic Splenic Compression of the Kidney in a Patient with Chronic Lymphocytic LeukemiaMiriam Hadj-Moussa0James A. Brown1Division of Urology, Medical College of Georgia, Augusta, GA, USADivision of Urology, Medical College of Georgia, Augusta, GA, USAWhile increased renal venous and direct renal parenchymal pressure may cause renal insufficiency, there are no prior reports of hypersplenism secondary to chronic lymphocytic leukemia (CLL) doing so. This first report of massive splenomegaly leading to marked compression of the left kidney associated with renal insufficiency that resolved after splenectomy illustrates that profound extrinsic renal compression from splenomegaly may significantly compromise left renal function and splenectomy should be considered in this situation.http://dx.doi.org/10.1100/tsw.2010.74
spellingShingle Miriam Hadj-Moussa
James A. Brown
Reversible Renal Insufficiency Secondary to Extrinsic Splenic Compression of the Kidney in a Patient with Chronic Lymphocytic Leukemia
The Scientific World Journal
title Reversible Renal Insufficiency Secondary to Extrinsic Splenic Compression of the Kidney in a Patient with Chronic Lymphocytic Leukemia
title_full Reversible Renal Insufficiency Secondary to Extrinsic Splenic Compression of the Kidney in a Patient with Chronic Lymphocytic Leukemia
title_fullStr Reversible Renal Insufficiency Secondary to Extrinsic Splenic Compression of the Kidney in a Patient with Chronic Lymphocytic Leukemia
title_full_unstemmed Reversible Renal Insufficiency Secondary to Extrinsic Splenic Compression of the Kidney in a Patient with Chronic Lymphocytic Leukemia
title_short Reversible Renal Insufficiency Secondary to Extrinsic Splenic Compression of the Kidney in a Patient with Chronic Lymphocytic Leukemia
title_sort reversible renal insufficiency secondary to extrinsic splenic compression of the kidney in a patient with chronic lymphocytic leukemia
url http://dx.doi.org/10.1100/tsw.2010.74
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AT jamesabrown reversiblerenalinsufficiencysecondarytoextrinsicspleniccompressionofthekidneyinapatientwithchroniclymphocyticleukemia