Prevalence of Latent Autoimmune Diabetes of Adult (LADA) among Type2 Diabetes Mellitus (D.M.2) in Karbala

Objective: the aim of the study is to determine the prevalence of LADA among group of clinically diagnosed type 2 diabetes mellitus. Methodology: sample size equal to 280 patients with type 2 D.M. were subjected in this study, participating patients were consecutively recruited of Diabetes outpat...

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Main Authors: Sawsan M. AL-Hasnawi, Salman A. AL-Jiboury
Format: Article
Language:English
Published: University of Kufa, Faculty of Nursing 2015-04-01
Series:Kufa Journal for Nursing Sciences
Subjects:
Online Access:https://journal.uokufa.edu.iq/index.php/kjns/article/view/3153
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author Sawsan M. AL-Hasnawi
Salman A. AL-Jiboury
author_facet Sawsan M. AL-Hasnawi
Salman A. AL-Jiboury
author_sort Sawsan M. AL-Hasnawi
collection DOAJ
description Objective: the aim of the study is to determine the prevalence of LADA among group of clinically diagnosed type 2 diabetes mellitus. Methodology: sample size equal to 280 patients with type 2 D.M. were subjected in this study, participating patients were consecutively recruited of Diabetes outpatient clinic in AL-Hussein Teaching Hospital in Karbala of June, 2013 through January, 2014. A clinical questioner containing personal data, family history, type of diabetes, type of treatment, FBS, HA1C, BMI, diabetes duration & complications of diabetes. For analysis of data Prevalence of LADA among D.M.2 cases was calculated as the proportion of LADA cases in the D.M.2 cases. The Chi square test (X2) was used to assess the significance (P-value) of differences in frequencies of categorical variables. Results: prevalence of LADA among D.M.2 patients was 12.1%. A significant difference in family history, BMI, FBS, HA1C and duration of D.M was found between the studied groups. Conclusion: The prevalence of LADA is clinically underestimated among D.M2 patients and age of onset of diabetes should no longer be considered as a valid way to differentiate diabetes. Recommendation: the study recommends screening for islet cell autoantibodies as GAD65 for all patients with diabetes at onset or beginning of disease.
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spelling doaj-art-1ddfdd48fac5447ea7dfb16c8d8acc802025-08-20T03:10:20ZengUniversity of Kufa, Faculty of NursingKufa Journal for Nursing Sciences2223-40552521-86382015-04-015110.36321/kjns.vi20151.3153Prevalence of Latent Autoimmune Diabetes of Adult (LADA) among Type2 Diabetes Mellitus (D.M.2) in Karbala Sawsan M. AL-Hasnawi0Salman A. AL-Jiboury1University of KarbalaUniversity of Kufa Objective: the aim of the study is to determine the prevalence of LADA among group of clinically diagnosed type 2 diabetes mellitus. Methodology: sample size equal to 280 patients with type 2 D.M. were subjected in this study, participating patients were consecutively recruited of Diabetes outpatient clinic in AL-Hussein Teaching Hospital in Karbala of June, 2013 through January, 2014. A clinical questioner containing personal data, family history, type of diabetes, type of treatment, FBS, HA1C, BMI, diabetes duration & complications of diabetes. For analysis of data Prevalence of LADA among D.M.2 cases was calculated as the proportion of LADA cases in the D.M.2 cases. The Chi square test (X2) was used to assess the significance (P-value) of differences in frequencies of categorical variables. Results: prevalence of LADA among D.M.2 patients was 12.1%. A significant difference in family history, BMI, FBS, HA1C and duration of D.M was found between the studied groups. Conclusion: The prevalence of LADA is clinically underestimated among D.M2 patients and age of onset of diabetes should no longer be considered as a valid way to differentiate diabetes. Recommendation: the study recommends screening for islet cell autoantibodies as GAD65 for all patients with diabetes at onset or beginning of disease. https://journal.uokufa.edu.iq/index.php/kjns/article/view/3153GAD65LADAdiabetes mellitus
spellingShingle Sawsan M. AL-Hasnawi
Salman A. AL-Jiboury
Prevalence of Latent Autoimmune Diabetes of Adult (LADA) among Type2 Diabetes Mellitus (D.M.2) in Karbala
Kufa Journal for Nursing Sciences
GAD65
LADA
diabetes mellitus
title Prevalence of Latent Autoimmune Diabetes of Adult (LADA) among Type2 Diabetes Mellitus (D.M.2) in Karbala
title_full Prevalence of Latent Autoimmune Diabetes of Adult (LADA) among Type2 Diabetes Mellitus (D.M.2) in Karbala
title_fullStr Prevalence of Latent Autoimmune Diabetes of Adult (LADA) among Type2 Diabetes Mellitus (D.M.2) in Karbala
title_full_unstemmed Prevalence of Latent Autoimmune Diabetes of Adult (LADA) among Type2 Diabetes Mellitus (D.M.2) in Karbala
title_short Prevalence of Latent Autoimmune Diabetes of Adult (LADA) among Type2 Diabetes Mellitus (D.M.2) in Karbala
title_sort prevalence of latent autoimmune diabetes of adult lada among type2 diabetes mellitus d m 2 in karbala
topic GAD65
LADA
diabetes mellitus
url https://journal.uokufa.edu.iq/index.php/kjns/article/view/3153
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